8-hydroxy-2'-deoxyguanosine

DB02502ExperimentalSmall molecule

8-hydroxy-2'-deoxyguanosine: Overview.

Mechanism: Pharmacologically active on Ras-related C3 botulinum toxin substrate 1
Curator reviewed
Formula / weight: C₁₀H₁₃N₅O₅ · 283.2407 g/mol (avg)
Also known as: 8-Hydroxydeoxyguanosine · 8-OHdG · 8-Oxo-7,8-dihydro-2'-deoxyguanosine · 8-Oxo-dG · 8-Oxoguanosine

Resolves to

Compound

Structure

InChIKeyHCAJQHYUCKICQH-VPENINKCSA-NSMILESNC1=NC2=C(N=C(O)N2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1

Targets

What you can answer from here — as of September 19, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with 8-hydroxy-2'-deoxyguanosine, and which of those have an active Phase 3 trial?

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