(R)-methylmalonyl-CoA

DB04045InvestigationalSmall molecule

(R)-methylmalonyl-CoA: Overview.

Chemical structure of (R)-methylmalonyl-CoA
Formula / weight
C25H40N7O19P3S · 867.607 g/mol (avg)
Also known as
(R)-2-Methyl-3-oxopropanoyl-CoA · (R)-2-Methyl-3-oxopropionyl-CoA · (R)-3-Oxo-2-methylpropanoyl-CoA · Methylmalonyl-coenzyme A

Resolves to

Compound
ChEBI15465PubChem449534
Structure
InChIKeyMZFOKIKEPGUZEN-AGCMQPJKSA-NSMILESC[C@H](C(O)=O)C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
Targets
Q8GBW6Methylmalonyl-CoA carboxyltransferase 12S subunit

What you can answer from here — as of September 16, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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2Clinical trialsPhase, status and sponsor resolved per trial
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with (R)-methylmalonyl-CoA, and which of those have an active Phase 3 trial?

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