Benoxaprofen

DB04812ApprovedWithdrawnSmall molecule

The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets...

Chemical structure of Benoxaprofen
Mechanism
Curator reviewed
Formula / weight
C16H12ClNO3 · 301.724 g/mol (avg)
Code names
Lilly 90459

Resolves to

Compound
UNII17SZX404IMCAS51234-28-7ChEMBLCHEMBL340978ChEBI76114PubChem39941KEGGD03080
Clinical / RWD
ATCM01AE06PharmGKBPA166049178
Structure
InChIKeyMITFXPHMIHQXPI-UHFFFAOYSA-NSMILESCC(C(O)=O)C1=CC2=C(OC(=N2)C2=CC=C(Cl)C=C2)C=C1
Targets
P18054ALOX12P24752ACAT1

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1,659Drug interactionsStructured to mechanism, not free text
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1ATC codeIncluding every combination product, plus 23 drug categories
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9+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Benoxaprofen, and which of those have an active Phase 3 trial?

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