Methapyrilene

DB04819ApprovedWithdrawnSmall molecule

Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.

Chemical structure of Methapyrilene
Mechanism
Curator reviewed
Formula / weight
C14H19N3S · 261.39 g/mol (avg)
Also known as
Methypyrilene · Thenylpyramine
Code names
A-3322

Resolves to

Compound
UNIIA01LX40298CAS91-80-5ChEMBLCHEMBL1411979ChEBI6820PubChem8667KEGGC11114
Clinical / RWD
RxNorm6822ATCR06AC05
Structure
InChIKeyHNJJXZKZRAWDPF-UHFFFAOYSA-NSMILESCN(C)CCN(CC1=CC=CS1)C1=NC=CC=C1
Targets
P35367HRH1

What you can answer from here — as of September 16, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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701Drug interactionsStructured to mechanism, not free text
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1ATC codeIncluding every combination product, plus 16 drug categories
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6+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Methapyrilene, and which of those have an active Phase 3 trial?

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