JB991

DB05081ExperimentalSmall molecule

JB991 is a cyclopentenone prostaglandin analogue intended for treatment of psoriasis. The drug exerts marked antiproliferative and pro-apoptotic effect in human keratinocytes and fibroblasts in vitro. In addition a closely... In addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory effect in vivo in an animal model.

Primary indication
Investigated for use/treatment in psoriasis and psoriatic disorders and skin infections/disorders.Curator reviewed
Code names
JB991

Which companies are running trials of JB991, in which indications and phases, and which of those programs are still active?

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