TM30339 is an analogue of the natural hormone Pancreatic Polypeptide (PP), which is released in connection with meals. TM30339 works through the same receptor as the natural satiety hormone, Pancreatic... TM30339 thus imitates a natural mechanism, a satiety signal from the gastrointestinal system involved in the regulation of food intake in humans.
- Mechanism
- Curator reviewed
TM30339 works through the Y4 receptor like the natural satiety hormone, Pancreatic Polypeptide, PP, but TM30339 has improved properties over PP. Thus, TM30339 mimics a natural satiety signal from the gastrointestinal tract involved in the regulation of food intake in man. In pre-clinical studies in obese mice, the Y4 receptor selective TM30339 was highly efficacious with respect to long term body weight reduction.
- Primary indication
- Investigated for use/treatment in schizophrenia and schizoaffective disorders.Curator reviewed
- Code names
- TM30339
Resolves to
What you can answer from here — as of June 15, 2026
Which drugs share a target with TM30339, and which of those have an active Phase 3 trial?
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