ARC183

Identification

Generic Name: ARC183
DrugBank Accession Number: DB05124
Background: ARC183 is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity and specificity. The key advantage of ARC183 compared to other thrombin inhibitors is its rapid onset of action and short half-life, giving it the potential to be an ideal agent for medical procedures that require rapid resolution of anticoagulation or that require reversal of anticoagulation shortly after the procedure is completed.
Type: Biotech
Groups: Investigational
Biologic Classification: Nucleic Acid Based Therapies
Oligonucleotides
Synonyms: Not Available

Indication: Investigated for use/treatment in blood (blood forming organ disorders, unspecified), cardiac surgery, and coronary artery disease.

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Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs: Not Available

Drug Interactions: This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions: Not Available

General References

Not Available

External Links

Clinical Trials

Phase	Status	Purpose	Conditions	Count

Drug created at October 21, 2007 22:23 / Updated at August 26, 2022 21:50