DB05151ExperimentalSmall molecule
TST10088 is a recombinant variant of a plant toxin belonging to the family of class II ribosome inactivating proteins. These molecules efficiently kill cells by activating preprogrammed death pathways known... TST10088 has been designed and engineered by Twinstrand to contain a peptide switch that is specifically cleaved by the matrix metalloproteinases which are known to be involved in tumor growth and metastasis.
- Primary indication
- Investigated for use/treatment in solid tumors.Curator reviewed
- Code names
- TST10088
Which companies are running trials of TST10088, in which indications and phases, and which of those programs are still active?
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