NCX 701

DB05409ExperimentalSmall molecule

Nitroparacetamol (NCX-701) is a newly synthesized nitric oxide-releasing derivative of paracetamol.

Mechanism: NCX-701 (nitroparacetamol) is a NO-releasing derivative of paracetamol (acetaminophen) that has shown potent antinociceptive and anti-inflammatory properties. NCX-701 induces a potent antinociceptive effect by a mechanism different from and complementary to that of paracetamol, and its action is mainly located within the spinal cord in monoarthritic animals.
Curator reviewed
Primary indication: Investigated for use/treatment in pain (acute or chronic).Curator reviewed
Formula / weight: C₁₂H₁₄N₂O₆ · 282.2494 g/mol (avg)
Code names: NCX 701

Resolves to

Compound

Structure

InChIKeyXTMOQAKCOFLCRZ-UHFFFAOYSA-NSMILESCC(=O)NC1=CC=C(OC(=O)CCCO[N+]([O-])=O)C=C1

Targets

What you can answer from here — as of April 02, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with NCX 701, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.