Verubulin

DB05585InvestigationalSmall molecule

Antineoplastic; a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps.

Chemical structure of Verubulin
Mechanism
Curator reviewed
Primary indication
Investigated for use/treatment in brain cancer, lung cancer, melanoma, and solid tumors.Curator reviewed
Formula / weight
C17H17N3O · 279.343 g/mol (avg)
Also known as
Varbulin
Code names
MX-128495

Resolves to

Compound
UNIIX97O9FTB92CAS827031-83-4ChEMBLCHEMBL492399
Structure
InChIKeySNHCRNMVYDHVDT-UHFFFAOYSA-NSMILESCOC1=CC=C(C=C1)N(C)C1=NC(C)=NC2=C1C=CC=C2

What you can answer from here — as of September 21, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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6Clinical trialsPhase, status and sponsor resolved per trial
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6+ReferencesStructured and connected to the statements they support
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Which companies are running trials of Verubulin, in which indications and phases, and which of those programs are still active?

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