R112

DB06252ExperimentalSmall molecule

R112 is an investigational compound developed to treat Allergic Rhinitis. It's mechanism of action is to inhibit SYK kinase.

Mechanism: Pharmacologically active on Tyrosine-protein kinase SYK
Curator reviewed
Primary indication: Investigated for use/treatment in allergic rhinitis.Curator reviewed
Formula / weight: C₁₆H₁₃FN₄O₂ · 312.304 g/mol (avg)
Also known as: 3-((5-FLUORO-2-(3-HYDROXYANILINO)PYRIMIDIN-4-YL)AMINO)PHENOL · 3,3'-((5-FLUORO-2,4-PYRIMIDINEDIYL)DIIMINO)BIS(PHENOL) · PHENOL, 3,3'-((5-FLUORO-2,4-PYRIMIDINEDIYL)DIIMINO)BIS-
Code names: R-921218

Resolves to

Compound

Structure

InChIKeyTVKGTSHBQZEFEE-UHFFFAOYSA-NSMILESOC1=CC=CC(NC2=NC=C(F)\C(N2)=N/C2=CC(O)=CC=C2)=C1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with R112, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.