Sonepcizumab

DB06305InvestigationalProtein Based Therapies

A humanized monoclonal antibody directed against sphingosine 1-phosphate (S1P) with potential antiangiogenic and antineoplastic activities. Upon administration, sonepcizumab binds S1P, which may result in the inhibition of tumor angiogenesis. S1P... S1P is the extracellular ligand for the G protein-coupled lysophospholipid receptor EDG-1 (endothelial differentiation gene-1).

Protein structure of Sonepcizumab
Primary indication
Investigated for use/treatment in solid tumors.Curator reviewed
Code names
LT-1009

Resolves to

What you can answer from here — as of June 12, 2020

381Drug interactionsStructured to mechanism, not free text
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5Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which companies are running trials of Sonepcizumab, in which indications and phases, and which of those programs are still active?

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