FK-960

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
FK-960
DrugBank Accession Number
DB06465
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 265.288
Monoisotopic: 265.12265493
Chemical Formula
C13H16FN3O2
Synonyms
  • N-(4-Acetyl-1-piperazinyl)-4-fluorobenzamide
External IDs
  • FK 960
  • FK-960
  • FK960

Pharmacology

Indication

Investigated for use/treatment in dementia, alzheimer's disease, schizophrenia and schizoaffective disorders, and memory loss.

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
60MMJ100ZX
CAS number
133920-70-4
InChI Key
XTOKQKWTUYYVAO-UHFFFAOYSA-N
InChI
InChI=1S/C13H16FN3O2/c1-10(18)16-6-8-17(9-7-16)15-13(19)11-2-4-12(14)5-3-11/h2-5H,6-9H2,1H3,(H,15,19)
IUPAC Name
N-(4-acetylpiperazin-1-yl)-4-fluorobenzamide
SMILES
CC(=O)N1CCN(CC1)NC(=O)C1=CC=C(F)C=C1

References

General References
Not Available
ChemSpider
157826
ZINC
ZINC000000006740

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility4.11 mg/mLALOGPS
logP0.22ALOGPS
logP-0.09Chemaxon
logS-1.8ALOGPS
pKa (Strongest Acidic)14.31Chemaxon
pKa (Strongest Basic)-0.31Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area52.65 Å2Chemaxon
Rotatable Bond Count2Chemaxon
Refractivity68.77 m3·mol-1Chemaxon
Polarizability26.41 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-01b9-0090000000-ca05c210cc2bb2565122
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-03di-0090000000-ccb0eb0b18183515e8d5
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-014i-0490000000-c6c7c35eb59bcbc3634c
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0007-9420000000-1ca6d2423e52b2230260
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-00di-4910000000-5c00e7c4f174abe39c57
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-9820000000-f286ca935c5c2693a54a
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at March 19, 2008 16:34 / Updated at June 12, 2020 16:52