Manganese cation is a transition metal used for supplementation of manganese during Total Parenteral Nutrition (TPN). Manganese is a transition metal that was first described in the 19th and 20th centuries.
- Mechanism
- Curator reviewed · 6 references
Mn2+ is an essential cofactor and activator for many enzymes that regulate biological functions and processes, such as oxidoreductases, transferases, hydrolases, lyases, isomerases, and ligases. These enzymes include polysaccharide polymerase, liver arginase, cholinesterase, pyruvate carboxylase, and Mn superoxide dismutase (MnSOD). These enzymes regulate immune function, metabolism, growth potential, hemostasis, mitochondrial homeostasis and antioxidant function, and neuronal function.
- Primary indication
- Intravenous manganese, alone or in combination with other trace elements, is indicated for total parenteral nutrition (TPN).Curator reviewed · 7 structured indications
- Formula / weight
- Mn · 54.938 g/mol (avg)
- First approval
- Canada, 1996 · United States, 2005
- Also known as
- MANGANESE CATION (2+) · MANGANESE CATION (MN2+) · MANGANESE DICATION · MANGANESE ION(2+) · MANGANESE, ION (MN2+)
- Brand names
Resolves to
WAEMQWOKJMHJLA-UHFFFAOYSA-NSMILES[Mn++]What you can answer from here — as of September 13, 2026
Which drugs share a target with Manganese cation, and which of those have an active Phase 3 trial?
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