Sulfamoxole

DB08798ExperimentalSmall molecule

Sulfamoxole is an antibacterial in the sulfonamide class.

Mechanism: Sulfamoxole is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. This enzyme is needed for the proper processing of para-aminobenzoic acid (PABA) which is essential for folic acid synthesis. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.
Curator reviewed
Primary indication: For the treatment of bacterial infection.Curator reviewed
Formula / weight: C₁₁H₁₃N₃O₃S · 267.304 g/mol (avg)
Also known as: Oxasulfa · Sulfadimethyloxazole · Sulphamoxole

Resolves to

Compound

UNIIHGG82XE020CAS729-99-7ChEMBLCHEMBL2105399ChEBI55548PubChem12894KEGGD02516

Clinical / RWD

RxNorm10183ATCJ01EC03ATCJ01EE04PharmGKBPA165958417

Structure

InChIKeyCYFLXLSBHQBMFT-UHFFFAOYSA-NSMILESCC1=C(C)N=C(NS(=O)(=O)C2=CC=C(N)C=C2)O1

Targets

Q27738dihydropteroate synthase

What you can answer from here — as of February 21, 2021

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

309Drug interactionsStructured to mechanism, not free text

2ATC codesIncluding every combination product, plus 17 drug categories

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Sulfamoxole, and which of those have an active Phase 3 trial?

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