Identification
- Generic Name
- Iodamide
- DrugBank Accession Number
- DB08948
- Background
Iodamide is a contrast medium molecule that is no longer marketed in the United States.
- Type
- Small Molecule
- Groups
- Withdrawn
- Structure
Structure for Iodamide (DB08948)
- Weight
- Average: 627.9402
Monoisotopic: 627.78528711 - Chemical Formula
- C12H11I3N2O4
- Synonyms
- Ametriiodic acid
- Ametriiodinic acid
- Ametriodinic acid
- Iodamida
- Iodamide
- Iodamidum
- Urombrine
- External IDs
- B 4130
- B-4130
- SH 926
- SH-926
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key Iodamide meglumine 6X283535A3 18656-21-8 UYIPQECISAQMIU-WZTVWXICSA-N - International/Other Brands
- Angiomiron (Schering) / Jodomiron / Renovue / Uromiro / Uromiron (Schering)
Categories
- ATC Codes
- V08AA03 — Iodamide
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as halobenzoic acids. These are benzoic acids carrying a halogen atom on the benzene ring.
- Kingdom
- Organic compounds
- Super Class
- Benzenoids
- Class
- Benzene and substituted derivatives
- Sub Class
- Benzoic acids and derivatives
- Direct Parent
- Halobenzoic acids
- Alternative Parents
- 2-halobenzoic acids / 4-halobenzoic acids / Benzoic acids / 1-carboxy-2-haloaromatic compounds / Benzoyl derivatives / Iodobenzenes / Aryl iodides / Vinylogous halides / Monocarboxylic acids and derivatives / Carboximidic acids show 7 more
- Substituents
- 1-carboxy-2-haloaromatic compound / 2-halobenzoic acid / 2-halobenzoic acid or derivatives / 4-halobenzoic acid / 4-halobenzoic acid or derivatives / Aromatic homomonocyclic compound / Aryl halide / Aryl iodide / Benzoic acid / Benzoyl show 20 more
- Molecular Framework
- Aromatic homomonocyclic compounds
- External Descriptors
- organoiodine compound, benzoic acids (CHEBI:31703)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 4RII332O0R
- CAS number
- 440-58-4
- InChI Key
- VVDGWALACJEJKG-UHFFFAOYSA-N
- InChI
- InChI=1S/C12H11I3N2O4/c1-4(18)16-3-6-8(13)7(12(20)21)10(15)11(9(6)14)17-5(2)19/h3H2,1-2H3,(H,16,18)(H,17,19)(H,20,21)
- IUPAC Name
- 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodobenzoic acid
- SMILES
- CC(=O)NCC1=C(I)C(NC(C)=O)=C(I)C(C(O)=O)=C1I
References
- General References
- Not Available
- External Links
- KEGG Drug
- D01376
- PubChem Compound
- 3723
- PubChem Substance
- 310264914
- ChemSpider
- 3592
- 5928
- ChEBI
- 31703
- ChEMBL
- CHEMBL1201239
- ZINC
- ZINC000003830933
- Drugs.com
- Drugs.com Drug Page
- Wikipedia
- Iodamide
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Solution Intravesical Injection, solution Intravenous - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0577 mg/mL ALOGPS logP 2.55 ALOGPS logP 2.6 Chemaxon logS -4 ALOGPS pKa (Strongest Acidic) 2.28 Chemaxon pKa (Strongest Basic) -1.8 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 95.5 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 106.18 m3·mol-1 Chemaxon Polarizability 40.78 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 191.68378 predictedDeepCCS 1.0 (2019) [M+H]+ 194.37132 predictedDeepCCS 1.0 (2019) [M+Na]+ 202.16362 predictedDeepCCS 1.0 (2019)
Drug created at May 27, 2014 17:35 / Updated at February 02, 2024 22:54