Ifenprodil

DB08954ApprovedInvestigationalWithdrawnSmall molecule

N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function. NMDARs are heterotetramers that typically involve a dimer of... NMDARs are heterotetramers that typically involve a dimer of dimers of both GluN1 and GluN2A-D subunits, with each subunit itself composed of an N-terminal domain (NTD), a ligand-binding domain (LBD), a transmembrane domain, and a...

Chemical structure of Ifenprodil
Mechanism
Curator reviewed
Formula / weight
C21H27NO2 · 325.4446 g/mol (avg)
Code names
NP-120 · RC 61-91 · RC 61-96

Resolves to

Compound
UNIIR8OE3P6O5SCAS23210-56-2ChEMBLCHEMBL305187ChEBI93829PubChem3689KEGGD08064
Clinical / RWD
RxNorm27403ATCC04AX28
Structure
InChIKeyUYNVMODNBIQBMV-UHFFFAOYSA-NSMILESCC(C(O)C1=CC=C(O)C=C1)N1CCC(CC2=CC=CC=C2)CC1
Targets
Q13224GRIN2BQ05586GRIN1Q9UNI1CELA1P48549KCNJ3P48051KCNJ6P48544KCNJ5

What you can answer from here — as of September 16, 2026

6Protein targetsEach mapped to UniProt, with action and pharmacological action
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1,202Drug interactionsStructured to mechanism, not free text
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4Clinical trialsPhase, status and sponsor resolved per trial
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1ATC codeIncluding every combination product, plus 15 drug categories
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20+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Ifenprodil, and which of those have an active Phase 3 trial?

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