Dimetacrine

DB08996ApprovedWithdrawnSmall molecule

Dimetacrine is also known as dimethacrine or acripamine. It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. Dimetacrine is a tricyclic antidepressant (TCA) with imipramine-like effects used in...

Chemical structure of Dimetacrine
Mechanism
Curator reviewed
Formula / weight
C20H26N2 · 294.4338 g/mol (avg)
Also known as
Istonil · Istonyl · Linostil · Miroistonil

Resolves to

Compound
UNIIO341NY501NCAS4757-55-5ChEMBLCHEMBL1328913ChEBI135233PubChem94280KEGGD02565
Clinical / RWD
ATCN06AA18
Structure
InChIKeyRYQOGSFEJBUZBX-UHFFFAOYSA-NSMILESCN(C)CCCN1C2=CC=CC=C2C(C)(C)C2=CC=CC=C12
Targets
P22303ACHE

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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1,770Drug interactionsStructured to mechanism, not free text
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1ATC codeIncluding every combination product, plus 12 drug categories
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Dimetacrine, and which of those have an active Phase 3 trial?

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