Bromopride

DB09018InvestigationalSmall molecule

Bromopride is a substituted benzamide, closely related to metoclopramide, used as an antiemetic. Its prokinetic properties are similar to those of metoclopramide.

Chemical structure of Bromopride
Mechanism
Curator reviewed
Primary indication
Bromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the GI tract.Curator reviewed · 15 structured indications
Formula / weight
C14H22BrN3O2 · 344.247 g/mol (avg)
Code names
VAL 13081

Resolves to

Compound
UNII75473V2YZKCAS4093-35-0ChEMBLCHEMBL399510ChEBI95304PubChem2446KEGGD07101
Clinical / RWD
RxNorm19768ATCA03FA04
Structure
InChIKeyGIYAQDDTCWHPPL-UHFFFAOYSA-NSMILESCCN(CC)CCNC(=O)C1=CC(Br)=C(N)C=C1OC
Targets
P14416DRD2

What you can answer from here — as of May 27, 2021

1Protein targetEach mapped to UniProt, with action and pharmacological action
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27Drug interactionsStructured to mechanism, not free text
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1Clinical trialPhase, status and sponsor resolved per trial
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15Structured indicationsCondition, population, route and combination as fields, not prose
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2ContraindicationsEach with its own population and attribute set
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8Marketed productsAcross 2 countries and 3 labellers
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1ATC codeIncluding every combination product, plus 25 drug categories
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Bromopride, and which of those have an active Phase 3 trial?

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