Mirfentanil

DB09175ExperimentalSmall molecule

Mirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor. At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in... At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in morphine-treated monkeys; however, it also reverses naloxone-precipitated withdrawal in pigeons trained to discriminate morphine from naloxone.

Mechanism: Pharmacologically active on Mu-type opioid receptor
Curator reviewed
Formula / weight: C₂₂H₂₄N₄O₂ · 376.46 g/mol (avg)

Resolves to

Compound

UNIIQ2U943H24PCAS117523-47-4ChEMBLCHEMBL161084PubChem60698

Structure

InChIKeyBJZZDOLVVLWFHN-UHFFFAOYSA-NSMILESO=C(N(C1CCN(CCC2=CC=CC=C2)CC1)C1=NC=CN=C1)C1=CC=CO1

Targets

P35372OPRM1

What you can answer from here — as of July 03, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Mirfentanil, and which of those have an active Phase 3 trial?

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