Cirazoline

DB09202ExperimentalSmall molecule

Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. It is believed... It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent.

Mechanism: Pharmacologically active on Alpha-1A adrenergic receptor, Alpha-1B adrenergic receptor, and Alpha-1D adrenergic receptor
Curator reviewed
Formula / weight: C₁₃H₁₆N₂O · 216.284 g/mol (avg)

Resolves to

Compound

UNIIQK318GVY3YCAS59939-16-1ChEMBLCHEMBL13852ChEBI92950PubChem2765

Structure

InChIKeyYAORIDZYZDUZCM-UHFFFAOYSA-NSMILES[H]N1CCN=C1COC1=CC=CC=C1C1CC1

Targets

P35348ADRA1AP35368ADRA1BP25100ADRA1DP18825ADRA2C

What you can answer from here — as of January 29, 2025

5Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

690Drug interactionsStructured to mechanism, not free text

20+ReferencesStructured and connected to the statements they support

Which drugs share a target with Cirazoline, and which of those have an active Phase 3 trial?

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