Mebanazine

DB09248ApprovedWithdrawnSmall molecule

Mebanazine, also known as Actomol, is a monoamine oxidase inhibitor (MAOI) belonging to the hydrazine class of chemicals. It was used in the past as an antidepressant in the 1960s,... It was used in the past as an antidepressant in the 1960s, but has since been discontinued because of its hepatotoxic potential.

Mechanism: Pharmacologically active on Monoamine oxidase
Curator reviewed
Primary indication: For the treatment of depression.Curator reviewed
Formula / weight: C₈H₁₂N₂ · 136.198 g/mol (avg)

Resolves to

Compound

UNIIZ5R55CJ4CGCAS65-64-5ChEMBLCHEMBL1909283ChEBI134728PubChem6179

Structure

InChIKeyHHRZAEJMHSGZNP-UHFFFAOYSA-NSMILESCC(NN)C1=CC=CC=C1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1,661Drug interactionsStructured to mechanism, not free text

8+ReferencesStructured and connected to the statements they support

Which companies are running trials of Mebanazine, in which indications and phases, and which of those programs are still active?

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