Pheniprazine

DB09250ApprovedWithdrawnSmall molecule

Pheniprazine is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant in the 1960s. In addition, it was used for... In addition, it was used for the treatment of other conditions, such as angina pectoris and schizophrenia.

Mechanism: Pharmacologically active on Amine oxidase [flavin-containing] B, Amine oxidase [flavin-containing] A, and Monoamine oxidase
Curator reviewed
Primary indication: For the treatment of depression, schizophrenia, and angina pectoris.Curator reviewed
Formula / weight: C₉H₁₄N₂ · 150.225 g/mol (avg)

Resolves to

Compound

UNII37VKD7067MCAS55-52-7ChEMBLCHEMBL22498ChEBI134773PubChem5929

Structure

InChIKeyVXTWEDPZMSVFEF-UHFFFAOYSA-NSMILESCC(CC1=CC=CC=C1)NN

Targets

P27338MAOBP21397MAOA

What you can answer from here — as of August 30, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1,331Drug interactionsStructured to mechanism, not free text

12+ReferencesStructured and connected to the statements they support

Which drugs share a target with Pheniprazine, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account