Phenoxypropazine

DB09251ApprovedWithdrawnSmall molecule

Phenoxypropazine is a non-selective and irreversible monoamine oxidase enzyme inhibitor (MAOI), belonging to the hydrazine chemical class. It was marketed as an antidepressant in 1961 but was later withdrawn in...

Mechanism: Pharmacologically active on Monoamine oxidase
Curator reviewed
Primary indication: For the treatment of depression.Curator reviewed
Formula / weight: C₉H₁₄N₂O · 166.224 g/mol (avg)
Also known as: (1-METHYL-2-PHENOXYETHYL)HYDRAZINE · Fenoxypropazine · HYDRAZINE, (1-METHYL-2-PHENOXYETHYL)-

Resolves to

Compound

UNII8E92V52324CAS3818-37-9ChEMBLCHEMBL1909286ChEBI134799PubChem71467

Structure

InChIKeyQNEXFJFTGQBXBJ-UHFFFAOYSA-NSMILES[H]N([H])N([H])C(C)COC1=CC=CC=C1

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1,661Drug interactionsStructured to mechanism, not free text

8+ReferencesStructured and connected to the statements they support

Which companies are running trials of Phenoxypropazine, in which indications and phases, and which of those programs are still active?

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