Carindacillin is a penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA. Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin.
- Mechanism
- Curator reviewed
Pharmacologically active on Penicillin-binding protein
- Primary indication
- For the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria (due to susceptible strains Escherichia coli, Proteus mirabilis, Morganella morganii, Providencia rettgeri, Proteus vulgaris, Pseudomonas, Enterobacter,...Curator reviewed
- Formula / weight
- C26H26N2O6S · 494.56 g/mol (avg)
- First approval
- United States, 1972
- Also known as
- Carbenicillin indanyl · Indanyl carbenicillin
Resolves to
Clinical / RWD
Structure
InChIKey
JIRBAUWICKGBFE-MNRDOXJOSA-NSMILES[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C(C(=O)OC1=CC2=C(CCC2)C=C1)C1=CC=CC=C1)C(O)=OWhat you can answer from here — as of September 16, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
Which companies are running trials of Carindacillin, in which indications and phases, and which of those programs are still active?
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