Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12... When vitamin B12 is provided in combination with intrinsic factor, intrinsic factor reduces protease degradation and increases absorption of Vitamin B12.
- Mechanism
- Curator reviewed
Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine. When vitamin B12 is provided in combination with intrinsic factor, intrinsic factor reduces protease degradation and increases absorption of Vitamin B12.
- Primary indication
- Intrinsic factor is not currently available in any FDA or Health Canada approved products.Curator reviewed
- Also known as
- Intrinsic factor
Resolves to
What you can answer from here — as of April 02, 2025
Which companies are running trials of Gastric intrinsic factor, in which indications and phases, and which of those programs are still active?
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