This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Iodohippurate sodium I-131
- DrugBank Accession Number
- DB09382
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved
- Structure
Structure for Iodohippurate sodium I-131 (DB09382)
- Weight
- Average: 331.055
Monoisotopic: 330.93848654 - Chemical Formula
- C9H7INNaO3
- Synonyms
- Iodohippurate sodium I 131
- Iodohippurate sodium I131
- Sodium iodohippurate (131 I)
- Sodium iodohippurate (131I)
Pharmacology
- Indication
Not Available
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- International/Other Brands
- Hippuran I131 / Hippuran-131 / Hipputope
Categories
- ATC Codes
- V09CX02 — Sodium iodohippurate (131i)
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as hippuric acids. These are compounds containing hippuric acid, which consists of a of a benzoyl group linked to the N-terminal of a glycine.
- Kingdom
- Organic compounds
- Super Class
- Benzenoids
- Class
- Benzene and substituted derivatives
- Sub Class
- Benzoic acids and derivatives
- Direct Parent
- Hippuric acids
- Alternative Parents
- N-acyl-alpha amino acids / 2-halobenzoic acids and derivatives / Benzoyl derivatives / Iodobenzenes / Aryl iodides / Vinylogous halides / Secondary carboxylic acid amides / Carboxylic acid salts / Organic metal halides / Monocarboxylic acids and derivatives show 9 more
- Substituents
- 2-halobenzoic acid or derivatives / Alpha-amino acid or derivatives / Aromatic homomonocyclic compound / Aryl halide / Aryl iodide / Benzoyl / Carbonyl group / Carboxamide group / Carboxylic acid / Carboxylic acid derivative show 24 more
- Molecular Framework
- Aromatic homomonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 9BRV734R3E
- CAS number
- 881-17-4
- InChI Key
- XYITYKDGJLHYPW-UDYUCQKZSA-M
- InChI
- InChI=1S/C9H8INO3.Na/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13;/h1-4H,5H2,(H,11,14)(H,12,13);/q;+1/p-1/i10+4;
- IUPAC Name
- sodium 2-{[2-(¹³¹I)iodophenyl]formamido}acetate
- SMILES
- [Na+].[O-]C(=O)CNC(=O)C1=C([131I])C=CC=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 64825
- 91540
- ChEBI
- 134740
- ChEMBL
- CHEMBL1200763
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.324 mg/mL ALOGPS logP 1.51 ALOGPS logP 1.45 Chemaxon logS -3 ALOGPS pKa (Strongest Acidic) 2.65 Chemaxon pKa (Strongest Basic) -1.7 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 69.23 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 70.32 m3·mol-1 Chemaxon Polarizability 22.44 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available
Drug created at November 30, 2015 19:10 / Updated at June 12, 2020 17:42