Fluoride ion F-18 is a diagnostic radiopharmaceutical agent used as a bone imaging agent to delineate areas of altered osteogenesis. Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added.
- Mechanism
- Curator reviewed
18F-fluoride is a highly sensitive bone-seeking PET tracer used for detection of skeletal abnormalities. The uptake mechanism of 18F-fluoride has better pharmacokinetic characteristics (compared to other elements) including faster blood clearance and 2-fold higher uptake in bone. Uptake of 18F-fluoride reflects blood flow and bone remodeling.
- Primary indication
- 18F is used as a bone imaging agent to define areas of altered osteogenic activity.Curator reviewed · 2 structured indications
- Formula / weight
- F · 18.0015 g/mol (avg)
- First approval
- United States, 2009
- Also known as
- (18F)-Fluoride · 18F-Fluoride · Fluoride-18 anion
- Brand names
Resolves to
KRHYYFGTRYWZRS-BJUDXGSMSA-MSMILES[18F-]What you can answer from here — as of September 13, 2026
Which other approved drugs treat the same conditions as Fluoride ion F-18, and which companies have late-stage candidates in those indications?
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