Dipotassium phosphate is an ionic compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy. Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
- Mechanism
- Curator reviewed
Once phosphate gains access to the body fluids and tissues, it exerts little pharmacological effect. If the ion is introduced into the intestine, the absorbed phosphate is rapidly excreted. If large amounts are given by this route, much of it may escape absorption. Because this property leads to a cathartic action, phosphate salts are employed as mild laxatives.
- Primary indication
- Dipotassium phosphate is used in imitation dairy creamers, dry powder beverages, mineral supplements, and starter cultures as an additive.Curator reviewed · 8 structured indications
- Formula / weight
- HK2O4P · 174.1759 g/mol (avg)
- First approval
- Canada, 1996 · United States, 1988
- Also known as
- Di-potassium hydrogen phosphate · Dibasic potassium phosphate · Dipotassium acid phosphate · Dipotassium hydrogen monophosphate · Dipotassium hydrogen orthophosphate
- Code names
- 231-834-5 · E-340(II) · INS-340(II) · INS no.340(II)
- Brand names
Resolves to
ZPWVASYFFYYZEW-UHFFFAOYSA-LSMILES[K+].[K+].OP([O-])([O-])=OWhat you can answer from here — as of July 16, 2026
Which other approved drugs treat the same conditions as Dipotassium phosphate, and which companies have late-stage candidates in those indications?
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