This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Potassium lactate
- DrugBank Accession Number
- DB09483
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved
- Structure
Structure for Potassium lactate (DB09483)
- Weight
- Average: 128.1683
Monoisotopic: 127.987575887 - Chemical Formula
- C3H5KO3
- Synonyms
- Lactic acid, potassium salt
- Monopotassium 2-hydroxypropanoate
- Monopotassium lactate
- External IDs
- E-326
- E326
- INS NO.326
- INS-326
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Treatment of Decreased serum potassium levels •••••••••••• •••••••••• •••••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcebutolol Potassium lactate may increase the hyperkalemic activities of Acebutolol. Aceclofenac Potassium lactate may increase the hyperkalemic activities of Aceclofenac. Acemetacin Potassium lactate may increase the hyperkalemic activities of Acemetacin. Acetazolamide The risk or severity of dehydration can be increased when Acetazolamide is combined with Potassium lactate. Acetylsalicylic acid Potassium lactate may increase the hyperkalemic activities of Acetylsalicylic acid. - Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Active Moieties
Name Kind UNII CAS InChI Key Potassium cation ionic 295O53K152 24203-36-9 NPYPAHLBTDXSSS-UHFFFAOYSA-N - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Ionosol and Dextrose Potassium lactate (256 mg/100mL) + D-glucose monohydrate (5 g/100mL) + Potassium chloride (111 mg/100mL) + Sodium chloride (146 mg/100mL) + Sodium phosphate, monobasic, monohydrate (207 mg/100mL) Injection, solution Intravenous Hospira, Inc. 1986-05-08 2008-09-01 US 
Categories
- ATC Codes
- B05XA15 — Potassium lactate
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 276897E67U
- CAS number
- 996-31-6
- InChI Key
- PHZLMBHDXVLRIX-UHFFFAOYSA-M
- InChI
- InChI=1S/C3H6O3.K/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1
- IUPAC Name
- potassium 2-hydroxypropanoate
- SMILES
- [K+].CC(O)C([O-])=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 55189
- 314797
- ChEMBL
- CHEMBL1200664
- Wikipedia
- Potassium_lactate
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, solution Intravenous Injection, solution Parenteral Injection, solution Parenteral 2 MEQ Injection, solution Parenteral 2 MEQ/ML Injection, solution, concentrate Intravenous - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 786.0 mg/mL ALOGPS logP -0.63 ALOGPS logP -0.47 Chemaxon logS 0.79 ALOGPS pKa (Strongest Acidic) 3.78 Chemaxon pKa (Strongest Basic) -3.7 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 60.36 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 29.68 m3·mol-1 Chemaxon Polarizability 7.65 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 122.479904 predictedDeepCCS 1.0 (2019) [M+H]+ 125.27736 predictedDeepCCS 1.0 (2019) [M+Na]+ 133.53514 predictedDeepCCS 1.0 (2019)
Drug created at November 30, 2015 19:10 / Updated at May 21, 2021 10:21