Choline C-11 is an imaging agent used in positron emission tomography imaging for suspected recurrent prostate cancer and non-informative bone scintigraphy, computerized tomography, or magnetic resonance imaging. A medication used to improve the quality of images of the bones and prostate.
- Mechanism
- Curator reviewed
Choline C 11 Injection is a radiolabeled analog of choline, a precursor molecule essential for the biosynthesis of cell membrane phospholipids. Choline is involved in synthesis of the structural components of cell membranes, as well as modulation of trans-membrane signaling. Increased phospholipid synthesis (i.e., increased uptake of choline) has been associated with cell proliferation and the transformation process that occurs in tumor cells.
- Primary indication
- Choline C 11 Injection is indicated for positron emission tomography (PET) imaging of patients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized tomography (CT) or magnetic resonance imaging (MRI).Curator reviewed · 1 structured indication
- Formula / weight
- C5H14NO · 103.173 g/mol (avg)
- First approval
- United States, 2012
- Also known as
- (11)C-choline · Choline C11
Resolves to
OEYIOHPDSNJKLS-BJUDXGSMSA-NSMILESC[N+](C)([11CH3])CCOWhat you can answer from here — as of April 02, 2025
Which other approved drugs treat the same conditions as Choline C-11, and which companies have late-stage candidates in those indications?
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