Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Accession Number
DB10296
Description

Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 6a individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate.

Type
Biotech
Groups
Approved, Investigational
Biologic Classification
Vaccines
Conjugate
Synonyms
  • Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine

Pharmacology

Indication
Not Available
Associated Conditions
Contraindications & Blackbox Warnings
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Prevnar 13Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 6b capsular polysaccharide diphtheria crm197 protein conjugate antigen (4.4 ug/0.5mL) + Streptococcus pneumoniae type 7f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 9v capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL)Injection, suspensionIntramuscularA-S Medication Solutions2010-03-12Not applicableUS flag
Prevnar 13Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 mcg/0.5mL) + Corynebacterium diphtheriae (34 mcg/0.5mL) + Streptococcus pneumoniae type 1 capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 14 capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 18c capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 19a capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 19f capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 23f capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 3 capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 4 capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 5 capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 6b capsular polysaccharide antigen (4.4 mcg/0.5mL) + Streptococcus pneumoniae type 7f capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 9v capsular polysaccharide antigen (2.2 mcg/0.5mL)SuspensionIntramuscularPfizer Canada Ulc2010-03-01Not applicableCanada flag
Prevnar 13Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 6b capsular polysaccharide diphtheria crm197 protein conjugate antigen (4.4 ug/0.5mL) + Streptococcus pneumoniae type 7f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 9v capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL)Injection, suspensionIntramuscularWyeth Pharmaceutical Division of Wyeth Holdings LLC2010-03-12Not applicableUS flag

Categories

Drug Categories
Classification
Not classified

Chemical Identifiers

UNII
Z9HK08690W
CAS number
Not Available

References

General References
Not Available
PubChem Substance
347910482
RxNav
901633

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingPreventionChronic Kidney Disease (CKD)1
4CompletedDiagnosticImmune Response / Pneumonia / Streptococcus Pneumoniae1
4CompletedPreventionDiphtheria / Meningococcal / Pertussis Diseases / Streptococcal / Tetanus1
4CompletedTreatmentEnd Stage Renal Disease (ESRD)1
4RecruitingBasic ScienceHuman Immunodeficiency Virus (HIV) Infections / Human Immunodeficiency Virus Infection(HIV)/Acquired Immunodeficiency Syndrome (AIDS) / Human Immunodeficiency Virus Type 1 (HIV-1) Infection1
4RecruitingPreventionInfections, Pneumococcal / Infections, Streptococcus Pneumoniae / Invasive Pneumococcal Disease, Protection Against1
4RecruitingPreventionPlasma Cell Neoplasms1
3Active Not RecruitingPreventionInfections, Pneumococcal4
3Active Not RecruitingPreventionInfections, Pneumococcal / Vaccines, Pneumococcal1
3Active Not RecruitingTreatmentInfections, Pneumococcal1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SuspensionIntramuscular2.2 μg
Injection, suspensionIntramuscular
SuspensionIntramuscular
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on December 01, 2015 13:03 / Updated on September 24, 2020 05:24

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