Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Prevnar 13
Generic Name
Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
DrugBank Accession Number
DB10296
Background

Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 6a individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate.

Type
Biotech
Groups
Approved, Investigational
Biologic Classification
Vaccines
Conjugate
Synonyms
  • Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
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Not Available
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTORStreptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 19f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 6b capsular polysaccharide diphtheria crm197 protein conjugate antigen (4.4 μg) + Streptococcus pneumoniae type 7f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 9v capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg)SuspensionIntramuscularPFİZER PFE İLAÇLARI A.Ş.2020-08-14Not applicableTurkey flag
PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR, 10 ADETStreptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 19f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 6b capsular polysaccharide diphtheria crm197 protein conjugate antigen (4.4 μg) + Streptococcus pneumoniae type 7f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 9v capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg)SuspensionIntramuscularPFİZER PFE İLAÇLARI A.Ş.2020-08-14Not applicableTurkey flag
PREVENAR 13/0,5 ML IM ENJEKSIYON ICIN SUS. ICEREN KUL.HAZIR ENJEKTOR, 50 ADETStreptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 19f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 6b capsular polysaccharide diphtheria crm197 protein conjugate antigen (4.4 μg) + Streptococcus pneumoniae type 7f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg) + Streptococcus pneumoniae type 9v capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 μg)SuspensionIntramuscularPFİZER İLAÇLARI LTD. ŞTİ.2020-08-14Not applicableTurkey flag
Prevnar 13Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 6b capsular polysaccharide diphtheria crm197 protein conjugate antigen (4.4 ug/0.5mL) + Streptococcus pneumoniae type 7f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 9v capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL)Injection, suspensionIntramuscularWyeth Pharmaceutical Division of Wyeth Holdings LLC2010-03-12Not applicableUS flag
Prevnar 13Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 mcg/0.5mL) + Corynebacterium diphtheriae (34 mcg/0.5mL) + Streptococcus pneumoniae type 1 capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 14 capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 18c capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 19a capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 19f capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 23f capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 3 capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 4 capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 5 capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 6b capsular polysaccharide antigen (4.4 mcg/0.5mL) + Streptococcus pneumoniae type 7f capsular polysaccharide antigen (2.2 mcg/0.5mL) + Streptococcus pneumoniae type 9v capsular polysaccharide antigen (2.2 mcg/0.5mL)SuspensionIntramuscularPfizer Canada Ulc2010-03-01Not applicableCanada flag
Prevnar 13Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 6b capsular polysaccharide diphtheria crm197 protein conjugate antigen (4.4 ug/0.5mL) + Streptococcus pneumoniae type 7f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 9v capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL)Injection, suspensionIntramuscularA-S Medication Solutions2010-03-12Not applicableUS flag
เพรฟนาร์ 13Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 6b capsular polysaccharide diphtheria crm197 protein conjugate antigen (4.4 ug/0.5mL) + Streptococcus pneumoniae type 7f capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 9v capsular polysaccharide diphtheria crm197 protein conjugate antigen (2.2 ug/0.5mL)SuspensionIntramuscularบริษัท ไฟเซอร์ (ประเทศไทย) จำกัด2013-07-31Not applicableThailand flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Z9HK08690W
CAS number
Not Available

References

General References
Not Available
PubChem Substance
347910482
RxNav
901633

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingPreventionChronic Kidney Disease (CKD)1
4CompletedBasic ScienceAging / Pneumonia1
4CompletedDiagnosticImmune Response / Pneumonia / Streptococcus Pneumoniae1
4CompletedPreventionBCG Infection / Immune Response / Vaccine Reaction1
4CompletedPreventionChronic Renal Failure (CRF)1
4CompletedPreventionCrohns Disease1
4CompletedPreventionMeningococcal1
4CompletedPreventionPneumococcal Infection / Thalassaemic disorders1
4CompletedPreventionRheumatoid Arthritis / Sjögren's Syndrome / Spondyloarthritis / Systemic Lupus / Systemic Vasculitis1
4CompletedTreatmentAsthma / Chronic Obstructive Pulmonary Disease (COPD) / Pneumococcal Infection1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SuspensionIntramuscular
Injection, suspensionIntramuscular
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on December 01, 2015 20:03 / Updated on September 24, 2020 11:24