Typhoid Vaccine Live

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Typhoid Vaccine Live
Accession Number
DB11050
Description

Salmonella typhi Ty21a live antigen is a live attenuated vaccine for oral administration only. It contains the attenuated strain Salmonella typhi Ty21a. The vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by Salmonella typhi by inducing a local immune response in the intestinal tract.

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Attenuated
Synonyms
  • Salmonella enterica subsp. enterica serovar typhi
  • Salmonella typhi Ty21a live antigen
  • Typhoid vaccine (salmonella typhi Ty21a)
  • Typhoid Vaccine Live Ty21a

Pharmacology

Indication
Not Available
Associated Conditions
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbacavirThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Abacavir.
AbataceptThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Abatacept.
AcyclovirThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Acyclovir.
AdalimumabThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Adalimumab.
Adefovir dipivoxilThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Adefovir dipivoxil.
AldesleukinThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Aldesleukin.
AlefaceptThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Alefacept.
AlemtuzumabThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Alemtuzumab.
AltretamineThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Altretamine.
AmantadineThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Amantadine.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

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Food Interactions
Not Available

Products

Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
VivotifCapsule, delayed release10000000000 [CFU]OralEmergent Biosolutions Berna Gmbh1993-01-01Not applicableCanada flag
VivotifCapsule, coated2 [CFU]/1[CFU]OralA-S Medication Solutions1992-03-16Not applicableUS flag
VivotifCapsule, coated6000000000 [CFU]/1OralA-S Medication Solutions1992-03-16Not applicableUS flag
VivotifCapsule, coated6000000000 [CFU]/1OralPaxvax Berna Gmbh1992-03-16Not applicableUS flag
Vivotif LPowderOralBerna Biotech Ltd1997-11-012015-11-01Canada flag
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Categories

Drug Categories
Classification
Not classified

Chemical Identifiers

UNII
760T5R8B3O
CAS number
Not Available

References

General References
Not Available
PubChem Substance
347911093
RxNav
762595
AHFS Codes
  • 80:12.00 — Vaccines

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingBasic ScienceFlu caused by Influenza / Healthy Adults / Hepatitis A / Salmonella Typhi Infection1
4RecruitingBasic ScienceRisk Reduction1
4RecruitingBasic ScienceTyphoid and/or Cholera Vaccination1
4RecruitingBasic ScienceTyphoid Vaccination1
4RecruitingPreventionHealthy Volunteers1
2Active Not RecruitingPreventionSalmonella Typhi Infection1
2TerminatedTreatmentUlcerative Colitis1
0Not Yet RecruitingBasic ScienceInflammatory Reaction / Intestinal Permeability / Salmonella Typhi Infection / Vaccines1
0RecruitingBasic ScienceInflammatory Reaction / Intestinal Permeability / Salmonella Typhi Infection / Vaccines1
Not AvailableCompletedNot AvailableSalmonella Typhi Infection1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Capsule, coatedOral2 [CFU]/1[CFU]
Capsule, coatedOral6000000000 [CFU]/1
Capsule, delayed releaseOral10000000000 [CFU]
PowderOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on December 01, 2015 13:05 / Updated on September 27, 2020 08:17

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