Typhoid Vaccine Live

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Vivotif
Generic Name
Typhoid Vaccine Live
DrugBank Accession Number
DB11050
Background

Salmonella typhi Ty21a live antigen is a live attenuated vaccine for oral administration only. It contains the attenuated strain Salmonella typhi Ty21a. The vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by Salmonella typhi by inducing a local immune response in the intestinal tract.

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Attenuated
Synonyms
  • Salmonella enterica subsp. enterica serovar typhi
  • Salmonella typhi Ty21a live antigen
  • Typhoid vaccine (salmonella typhi Ty21a)
  • Typhoid Vaccine Live Ty21a

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbacavirThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Abacavir.
AbataceptThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Abatacept.
AcyclovirThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Acyclovir.
AdalimumabThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Adalimumab.
Adefovir dipivoxilThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Adefovir dipivoxil.
AldesleukinThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Aldesleukin.
AlefaceptThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Alefacept.
AlemtuzumabThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Alemtuzumab.
AltretamineThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Altretamine.
AmantadineThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Amantadine.
Interactions
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Food Interactions
Not Available

Products

Products2
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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
VivotifCapsule, coated6000000000 [CFU]/1OralA-S Medication Solutions1992-03-16Not applicableUS flag
VivotifCapsule, coated6000000000 [CFU]/1OralEmergent Travel Health Inc.1992-03-16Not applicableUS flag
VivotifCapsule, delayed release10000000000 [CFU]OralEmergent Travel Health Inc.1993-01-01Not applicableCanada flag
VivotifCapsule, coated2 [CFU]/1[CFU]OralA-S Medication Solutions1992-03-16Not applicableUS flag
Vivotif LPowder10000000000 [CFU]OralBerna Biotech Ltd1997-11-012015-11-01Canada flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
760T5R8B3O
CAS number
Not Available

References

General References
Not Available
PubChem Substance
347911093
RxNav
762595

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingBasic ScienceFlu caused by Influenza / Healthy Adults / Hepatitis A / Salmonella Typhi Infection1
4RecruitingBasic ScienceRisk Reduction1
4RecruitingBasic ScienceTyphoid and/or Cholera Vaccination1
4RecruitingBasic ScienceTyphoid Vaccination1
4Unknown StatusPreventionHealthy Subjects (HS)1
2Active Not RecruitingPreventionSalmonella Typhi Infection1
2TerminatedTreatmentUlcerative Colitis1
0Not Yet RecruitingBasic ScienceInflammation / Intestinal Permeability / Salmonella Typhi Infection / Vaccines1
0RecruitingBasic ScienceInflammation / Intestinal Permeability / Salmonella Typhi Infection / Vaccines1
Not AvailableCompletedNot AvailableSalmonella Typhi Infection1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
CapsuleOral2000000000 CFU
Capsule, coatedOral2 [CFU]/1[CFU]
Capsule, coatedOral6000000000 [CFU]/1
Capsule, delayed releaseOral10000000000 [CFU]
Capsule, delayed releaseOral2000000000 U
CapsuleOral
Capsule, coatedOral
PowderOral10000000000 [CFU]
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on December 01, 2015 20:05 / Updated on September 25, 2021 16:29