Petrolatum
Identification
- Brand Names
- A+d Diaper Rash, Anbesol Cold Sore Therapy, Calazime Skin Protectant, Calmoseptine Ointment, DermaCerin, Flanders, Lubrifresh P.M., Periguard, Preparation H Cream, Preparation H Reformulated Jun 2013, Puralube, Refresh Lacri-lube, Refresh PM, Resinol, Soothe & Cool Skin Paste, Soothe Night Time, Stye, Systane, Systane Nighttime, Tears Again Ointment, Vusion, Zincofax
- Generic Name
- Petrolatum
- DrugBank Accession Number
- DB11058
- Background
A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
- Type
- Small Molecule
- Groups
- Approved, Investigational
- Synonyms
- Multi-hydrocarbon
- Paraffinum album
- Paraffinum flavum
- Petrolatum
- Petrolatum base
- Petrolatum, white
- Petrolatum,amber
- Petrolatum,white
- Petroleum jelly
- Soft paraffin
- White petrolatum
- White, soft paraffin
- Yellow soft paraffin
Pharmacology
- Indication
For use as an over the counter skin protectant Label. Commonly used to treat diaper rash and chapped lips Label 1.
Accelerate your drug discovery research with the industry’s only fully connected ADMET dataset, ideal for:Accelerate your drug discovery research with our fully connected ADMET dataset- Associated Conditions
- Associated Therapies
- Contraindications & Blackbox Warnings
Contraindications & Blackbox WarningsWith our commercial data, access important information on dangerous risks, contraindications, and adverse effects.Our Blackbox Warnings cover Risks, Contraindications, and Adverse Effects- Pharmacodynamics
Displaces water and acts as a barrier against harsh environmental conditions like wind Label 1.
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Reduce medical errorsand improve treatment outcomes with our comprehensive & structured data on drug adverse effects.Reduce medical errors & improve treatment outcomes with our adverse effects data- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Comprehensive & structured drug product infoFrom application numbers to product codes, connect different identifiers through our commercial datasets.Easily connect various identifiers back to our datasets- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image A and D Ointment 937.5 mg/1g Topical Henry Schein, Inc. 2011-12-04 Not applicable US 
A and D Ointment 0.93 g/1g Topical Gentell, Inc. 2019-05-25 Not applicable US A and D Ointment 937.5 mg/1g Topical H&H Laboratories, Inc. 2012-05-14 Not applicable US A and D Ointment 76 g/100g Topical Safetec of America, Inc. 2019-11-01 Not applicable US A and D plus E Ointment 937.5 mg/1g Topical H&H Laboratories, Inc. 2012-05-14 Not applicable US A and D plus E Ointment 0.9985 g/1g Topical Gentell, Inc. 2014-11-03 Not applicable US A and D plus E Ointment 0.9985 g/1g Topical Gentell, Inc. 2014-11-03 Not applicable US Advaced First Aid A and D Ointment 937.5 mg/1g Topical Advanced First Aid, Inc. 2015-04-07 Not applicable US Advanced Healing Ointment 340 mg/1g Topical Family Dollar Services Inc 2015-07-15 Not applicable US Advanced Healing Ointment 340 mg/100g Topical Walgreen Co 2013-08-27 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 7 Select Hemorrhoidal Original Strength Petrolatum (749 mg/1g) + Mineral oil (140 mg/1g) + Phenylephrine hydrochloride (2.5 mg/1g) Ointment Topical 7-ELEVEN, INC. 2016-12-07 Not applicable US A and D Diaper Rash and Skin Protectant Petrolatum (0.53 mg/1g) + Lanolin (0.15 mg/1g) Cream Topical Natureplex, LLC 2014-11-12 Not applicable US A and D First Aid Petrolatum (469.9 mg/1g) + Lanolin (136.4 mg/1g) Ointment Topical Bayer HealthCare LLC 2003-06-04 Not applicable US A and D First Aid Petrolatum (469.9 mg/1g) + Lanolin (136.4 mg/1g) Ointment Topical Delpharm Montreal Inc. 2003-06-04 Not applicable US A and D Original Petrolatum (469.9 mg/1g) + Lanolin (136.4 mg/1g) Ointment Topical Delpharm Montreal Inc. 2003-06-04 Not applicable US A and D Original Petrolatum (469.9 mg/1g) + Lanolin (136.4 mg/1g) Ointment Topical Bayer Healthcare Llc. 2003-06-04 Not applicable US A D and L Original Diaper Rash Skin Petrolatum (53.4 g/100g) + Lanolin (15.5 g/100g) Ointment Topical Harmon Stores 2014-09-01 Not applicable US A+d Diaper Rash Ointment Petrolatum (53.4 % w/w) + Lanolin (15.5 % w/w) Ointment Topical Schering Plough 1998-07-08 2014-07-31 Canada 
Abridge Cold Sore Treatment Petrolatum (892 mg/1g) + Camphor (30 mg/1g) + Levomenthol (10 mg/1g) + Phenol (15 mg/1g) Cream Topical Ranir LLC 2020-02-24 Not applicable US Alexander's Rash Ease - for Babies Petrolatum (88.7 %) + Zinc oxide (5 %) Cream Topical Altacomp Enterprises Inc 2010-05-29 Not applicable Canada - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Antiscar Petrolatum (3 g/100g) + 13-cis-12-(3'-Carboxyphenyl)retinoic acid (2 g/100g) + Allantoin (2 g/100g) + Epigallocatechin gallate (.3 g/100g) + Onion (.5 g/100g) Patch Topical Basiem 2015-04-01 2015-04-20 US Elite Petrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (4 g/100g) Patch Topical Meds Direct Rx Of Ny Llc 2015-01-31 2015-06-08 US Herpetrol Petrolatum (970 mg/1g) + Benzalkonium chloride (1.3 mg/1g) + Levomenthol (10 mg/1g) Ointment Topical Alva-Amco Pharmacal Companies, Inc. 2005-06-30 2018-01-31 US PCP 100 Kit Petrolatum (0.76 g/1g) + Bisacodyl (5 mg/1) + Magnesium citrate (1.745 g/29.6mL) + Metoclopramide hydrochloride (10 mg/1) + Polyethylene glycol (17 g/17g) Kit Oral Asclemed Usa, Inc. 2014-01-02 Not applicable US Preginot Petrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (4 g/100g) Patch Topical Pharmaco Technology Llc 2015-04-01 2015-04-01 US Premium Scar Patch Petrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (5 g/100g) Patch Topical Alivio Medical Products, Llc 2015-03-15 Not applicable US Renuu NL Petrolatum (30 g/100g) + Allantoin (2 g/100g) Patch Topical Patchwerx Labs 2014-04-15 Not applicable US Renuu Patch Petrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (5 g/100g) Patch Topical Patchwerx Labs 2014-04-15 Not applicable US Scar Patch Petrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine hydrochloride (4 g/100g) Patch Topical Binger Consulting Corporation 2014-12-01 2015-11-30 US Scar Patch Petrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (5 g/100g) Patch Topical Binger Consulting Corporation 2014-12-01 2016-07-31 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- B6E5W8RQJ4
- CAS number
- 8009-03-8
- InChI Key
- Not Available
- InChI
- Not Available
- IUPAC Name
- Not Available
- SMILES
- Not Available
References
- General References
- FDA Monograph: Petrolatum [Link]
- External Links
- KEGG Drug
- D05304
- PubChem Substance
- 347911097
- 8091
- Drugs.com
- Drugs.com Drug Page
- Wikipedia
- Petroleum_jelly
- AHFS Codes
- 84:24.12 — Basic Ointments and Protectants
- FDA label
- Download (230 KB)
- MSDS
- Download (47.7 KB)
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Active Not Recruiting Treatment Dry Skin / Type 2 Diabetes Mellitus 1 4 Completed Basic Science Inflammation 1 4 Completed Prevention Skin Diseases 1 4 Completed Treatment Atopic Dermatitis (AD) 1 4 Completed Treatment Diaper Dermatitis 1 4 Completed Treatment Diaper Rash 1 4 Completed Treatment Dry Eye Syndrome (DES) 1 4 Completed Treatment Dry Eye Syndromes 1 4 Completed Treatment Pityriasis Alba 1 4 Completed Treatment Scars, Hypertrophic 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Ointment Topical 0.93 g/1g Ointment Topical 937.5 mg/1g Ointment Topical 0.9985 g/1g Ointment Topical 340 mg/100g Cream Topical 54 g/100g Spray Topical 36 g/100g Ointment Topical 430 mg/1g Spray Topical 360 mg/1g Jelly Topical 99.8 g/100g Jelly Topical 99.5 g/100g Ointment Topical 100 g/44.28g Lotion Topical Ointment Topical 41 % Ointment Topical 540 mg/1g Ointment Topical 54 mg/1g Ointment Topical 60.1 % Paste Topical 74.69 % Ointment Topical 46.5 % w/w Cream Topical 99 g/100g Ointment Topical 99.93 % w/w Ointment Topical 84.3 g/100g Ointment Topical 84.3 % Ointment Topical 0.511 g/1g Ointment Topical 511 mg/1g Cream Topical 430 g/1000g Ointment Topical 960 mg/1g Ointment Topical 620 mg/1g Stick Topical Cream Topical 30 % Ointment Topical 34.85 g/85g Stick Topical 41 mg/1g Ointment Topical 43.75 mg/1g Ointment Topical .96 g/1g Salve Topical Cream Topical 0.61 g/1g Ointment Topical 46.5 g/100g Ointment Topical 715 mg/1g Cream Topical 13.2 % Lipstick Topical 619.3 mg/1g Stick Topical 450 mg/1g Kit Topical Gel Topical Stick Oral Jelly Topical Jelly Topical 1 g/1g Jelly Topical 998 mg/1g Salve Topical 27.6 g/28.4g Lotion Topical 5 g/100g Jelly Topical 30 g/100g Jelly Topical .30 g/100g Jelly Topical .30 mg/100g Cream Topical 30 g/100g Ointment Topical 710 mg/1g Ointment Topical 71.5 % w/w Ointment Topical 865 mg/1g Ointment Topical 98.3 % w/w Cream Topical 300 mg/1mL Ointment Topical 410 mg/1g Ointment Topical .041 g/.1g Cream Topical 33 g/100g Ointment Topical 70.3 % w/w Jelly Topical 99 g/100g Jelly Topical 98.3 g/100g Cream Topical 85 % Ointment Topical 85 g/100g Ointment Topical 33 g/100g Ointment Topical 44 g/100g Ointment Topical 713 mg/1g Ointment Topical 703.2 mg/1g Cream Topical 30 % w/w Ointment Topical 30 % Jelly Topical 226 g/226g Ointment Topical 124 g/207mL Ointment Ophthalmic Emulsion Topical 56.8 mg/1g Lotion Topical 28.4 g/50g Cream Topical 28.4 g/50g Cream Topical 56.8 mg/1g Gel Topical 1 g/85g Ointment Topical 600 g/1000g Ointment Topical 77.6 g/1000g Ointment Topical 0.41 g/1g Stick Topical 45.0 mg/1g Kit Ophthalmic Ointment Topical 40 g/100g Lipstick Topical Gel Topical 70.9787 g/71g Ointment Topical 87.32 g/118g Cream Rectal; Topical Ointment Topical 30 g/100g Ointment Topical 450 mg/1mL Cream Topical 50.74 g/100g Ointment Topical 340 mg/1g Ointment Topical 340 g/1g Ointment Topical 41 kg/1g Ointment Topical 41 kg/100kg Ointment Topical 46.5 % Stick Topical 670 mg/1g Ointment Rectal 93.3 g/100g Lipstick Topical 47.95 g/100g Liquid Topical 89.5 g/100g Ointment Topical 41.000 g/100g Ointment Topical 41 % w/w Cream Topical 45 g/100g Cream Topical 52.2 g/100g Gel Topical 300 mg/1mL Cream Topical 430 mg/1g Ointment Topical 430 mg/1mL Kit Not applicable Ointment Topical 76 g/100g Ointment Topical 48 g/100mL Stick Topical 32.3 g/100g Jelly Topical 1000 mg/1g Paste Topical Stick Topical 59.79 % Ointment Topical 935 mg/1g Ointment Rectal; Topical Ointment Topical 60.3 % w/w Ointment Topical 604 mg/1mL Ointment Topical 60.3 mL/100mL Spray Topical 36 g/120mL Spray Topical 36 mL/120mL Ointment Topical 69 % w/w Ointment Topical 99.397 g/100g Ointment Topical 99.9 g/100g Ointment Topical 774 mg/1g Cream Topical 95.96 % Ointment Topical 95.7 % w/w Stick Topical 45 mg/1g Ointment Topical 0.41 mg/1g Kit Oral Ointment Topical 49.9 g/100g Jelly Topical 170 g/170g Gel Topical 100 g/1g Cream Topical 69 mg/1g Ointment Topical 0.340 g/1g Ointment Topical 10 g/10g Ointment Topical 600 mg/1g Ointment Topical 100 % w/w Jelly Topical 1 mg/1g Jelly Topical 100 g/100g Jelly Topical 1000 mg/100g Jelly Topical 82.32 mg/1g Jelly Topical 838 g/1g Jelly Topical 99.8 g/100kg Jelly Topical Ointment Topical Ointment Topical 99.99 % w/w Jelly Topical 99.9 g/100g Jelly Topical 99.9 1/100g Jelly Topical 100 % Ointment Topical 99.6 % w/w Gel Topical 99.9 g/100g Paste 650 mg/1mL Cream Topical 67 % Ointment Topical 99.5 g/100g Ointment Topical 93.4 g/100g Ointment Topical 75 g/100g Ointment Topical 98.79 % w/w Ointment Topical 0.99 g/1g Cream Topical 0.6 g/1g Jelly Topical 0.99 g/1g Liquid Topical Ointment Topical 500 mg/1g Paste Topical 59 g/100g Paste Topical 57 g/100g Ointment Topical 83 mg/1g Ointment Topical 86 mg/1g Cream Topical 41 g/100g Jelly Topical 410 mg/1g Ointment Topical 41 g/100g Ointment Topical 420 mg/1g Jelly Topical 41.0 g/100g Ointment Topical 987.89 mg/1g Cream Rectal Cream Topical Gel Topical 99.98 mg/1g Cream Topical 43 g/100g Lotion Topical 39.9 g/133mL Ointment Topical 93.5 g/100g Cream Topical 43 g/1000g Ointment Topical 44.28 g/100g Ointment Topical 23 g/71g Jelly Topical 225 g/225g Jelly Topical 110 g/110g Solution Topical Ointment Topical 92.8 % Ointment Topical 92.8 g/100g Ointment Topical 98.3 g/100g Gel Ophthalmic Cream Topical 55 % Jelly Topical 99.7 g/100g Cream Cutaneous 65 g/100g Ointment Rectal Jelly Topical 99.6 g/100g Ointment Topical 99.96 % w/w Ointment Topical 100 g/100g Gel Topical 100 % Jelly Topical 99.96 g/100g Patch Topical Ointment Topical .948 mL/1mL Ointment Topical .948 g/1g Ointment Topical 0.948 mL/1mL Ointment Topical 30.8 g/56g Ointment Topical 929.3 mg/1g Ointment Topical .75 g/1g Ointment Topical .76 g/1g Ointment Topical 0.76 g/1g Ointment Topical .93 g/1g Ointment Topical 930 mg/1g Ointment Topical Ointment Topical 93 g/100g Lotion Topical 0.41 g/1g Ointment Topical 42 g/100g Ointment Topical 1 g/1g Ointment Topical 5 [USP'U]/5g Ointment Topical 50 g/100g Ointment Topical 100 % Ointment Topical 99.9 % Ointment Topical 1000 mg/1g Stick Topical 30.0 mg/1g Cream Topical 99.7 g/100g Jelly Topical 38 g/127g Cream Topical 59 g/198g Jelly Topical 100 kg/100kg - Prices
- Not Available
- Patents
Patent Number Pediatric Extension Approved Expires (estimated) Region US8147852 No 2012-04-03 2028-03-30 US
Properties
- State
- Solid
- Experimental Properties
Property Value Source melting point (°C) 38-60 MSDS water solubility Insoluble MSDS - Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created on December 03, 2015 16:51 / Updated on June 13, 2021 16:25