Shark liver oil

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Shark liver oil is an ingredient used to treat irritation associated with hemorrhoids and is not an approved medication.

Generic Name
Shark liver oil
DrugBank Accession Number
DB11088
Background

Shark oil is extracted from the livers of sharks, which can account for up to 25% of their total body weight. The 3 main targeted species are the deep sea shark (Centrophorus squamosus), the dogfish (Sqaulus acanthias), and the basking shark (Cetorhinus maximus). Shark oil is a rich source of alkylglycerols and squalene, with relatively low amounts of n-3 polyunsaturated fatty acids. However the major component is considered to be squalene, which may range up to 90% of the shark oil, depending on the species. The potential benefit of shark oil has been experimented in different therapeutic implications, where it is claimed to improve immune responses and exert an antitumor activity.

Type
Biotech
Groups
Experimental
Synonyms
Not Available

Pharmacology

Indication

Not Available

Pharmacology
Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Contraindications
Avoid life-threatening adverse drug events
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products2
Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Care One HemorrhoidalShark liver oil (3 g/100g) + Mineral oil (14 g/100g) + Petrolatum (71.9 g/100g) + Phenylephrine hydrochloride (0.25 g/100g)OintmentTopicalAmerican Sales Company2004-03-162014-08-30US flag
Care One HemorrhoidalShark liver oil (6.375 mg/1) + Cocoa butter (2137.5 mg/1) + Phenylephrine hydrochloride (75 mg/1)SuppositoryRectalAmerican Sales Company2003-12-092015-09-01US flag
Cocoa Butter, Phenylephrine Hydrochloride, Shark Liver OilShark liver oil (73 mg/1) + Cocoa butter (2077 mg/1) + Phenylephrine hydrochloride (6 mg/1)SuppositoryRectalH and P Industries, Inc. dba Triad Group2004-03-06Not applicableUS flag
DG Health HemorrhoidalShark liver oil (3 g/100g) + Mineral oil (14 g/100g) + Petrolatum (71.9 g/100g) + Phenylephrine hydrochloride (0.25 g/100g)OintmentTopicalDolgencorp2010-05-222014-10-16US flag
Equaline HemorrhoidalShark liver oil (6.375 mg/1) + Cocoa butter (2137.5 mg/1) + Phenylephrine hydrochloride (75 mg/1)SuppositoryRectalSupervalu2004-09-232015-09-01US flag
Equaline HemorrhoidalShark liver oil (3 g/100g) + Mineral oil (14 g/100g) + Petrolatum (71.9 g/100g) + Phenylephrine hydrochloride (0.25 g/100g)OintmentTopicalSupervalu2004-11-162011-09-16US flag
Equate hemorrhoidalShark liver oil (6.375 mg/1) + Cocoa butter (2137.5 mg/1) + Phenylephrine hydrochloride (75 mg/1)SuppositoryRectalWalmart Stores1998-03-062015-09-01US flag
Equate HemorrhoidalShark liver oil (3 g/100g) + Mineral oil (14 g/100g) + Petrolatum (71.9 g/100g) + Phenylephrine hydrochloride (0.25 g/100g)OintmentTopicalWalmart Stores1996-01-052014-10-28US flag
Family Care HemorrhoidalShark liver oil (30 mg/1g) + Mineral oil (140 mg/1g) + Petrolatum (719 mg/1g) + Phenylephrine hydrochloride (2.5 mg/1g)OintmentTopicalUnited Exchange Corporation2012-03-01Not applicableUS flag
Family wellness hemorrhoidalShark liver oil (3 g/100g) + Mineral oil (14 g/100g) + Petrolatum (71.9 g/100g) + Phenylephrine hydrochloride (0.25 g/100g)OintmentTopicalFamily Dollar Services2012-03-092013-11-21US flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
4B24275HEU
CAS number
68990-63-6

References

General References
  1. Lewkowicz N, Lewkowicz P, Kurnatowska A, Tchorzewski H: [Biological action and clinical application of shark liver oil]. Pol Merkur Lekarski. 2006 May;20(119):598-601. [Article]
PubChem Substance
347911111
RxNav
91472
Wikipedia
Shark_liver_oil

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
OintmentRectal; Topical
SuppositoryRectal
OintmentTopical14 %
SuppositoryRectal85.5 %
OintmentTopical
Prices
Not Available
Patents
Not Available

Properties

State
Liquid
Experimental Properties
Not Available

Drug created on December 03, 2015 16:51 / Updated on June 12, 2020 16:53