Panthenol is an ingredient used in skin, hair care, and nutritional products but is not an approved medication. Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.
- Mechanism
- Curator reviewed · 2 references
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium.
Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation and accelerated re-epithelialization in wound healing. Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties.
- Primary indication
- Panthenol (containing a racemic mixture of dexpanthenol and levopanthenol) is not currently available in any FDA-approved products and therefore does not have an indication.Curator reviewed · 2 structured indications
- Formula / weight
- C9H19NO4 · 205.254 g/mol (avg)
- First approval
- Canada, 2000
- Also known as
- DL-panthenol · DL-Pantothenol
Resolves to
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Which other approved drugs treat the same conditions as Panthenol, and which companies have late-stage candidates in those indications?
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