Amiloxate

DB11207ApprovedSmall molecule

Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is... Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity.

Mechanism: Amiloxate is a UV-B filter that selectively absorbs UV-B rays. It is proposed that amiloxate mediates an antioxidant action by acting as a free radical scavenger.
Curator reviewed · 2 references
Primary indication: Indicated as an active sunscreen agent.Curator reviewed · 1 structured indication
Formula / weight: C₁₅H₂₀O₃ · 248.322 g/mol (avg)
Also known as: Isoamyl p-methoxycinnamate
Code names: E-1000 · NSC-408332

Resolves to

Compound

UNII376KTP06K8CAS71617-10-2ChEMBLCHEMBL1476782

Clinical / RWD

RxNorm1426854

Structure

InChIKeyUBNYRXMKIIGMKK-RMKNXTFCSA-NSMILESCOC1=CC=C(\C=C\C(=O)OCCC(C)C)C=C1

What you can answer from here — as of February 21, 2021

1Clinical trialPhase, status and sponsor resolved per trial

1Structured indicationCondition, population, route and combination as fields, not prose

22Marketed productsAcross 1 country and 14 labellers

3+ReferencesStructured and connected to the statements they support

Which other approved drugs treat the same conditions as Amiloxate, and which companies have late-stage candidates in those indications?

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