Octacosanol
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Octacosanol
- DrugBank Accession Number
- DB11220
- Background
1-octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. This high–molecular-weight organic compound is the main component of a natural product wax extracted from plants 1. 1-octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytoprotective use, and ergogenic properties 1. It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease.
- Type
- Small Molecule
- Groups
- Nutraceutical
- Structure
Structure for Octacosanol (DB11220)
- Weight
- Average: 410.7595
Monoisotopic: 410.448766478 - Chemical Formula
- C28H58O
- Synonyms
- 1-Octacosanol
- cluytyl alcohol
- montanyl alcohol
- n-octacosanol
- Octacosanol
- Octacosyl alcohol
- External IDs
- NSC-10770
Pharmacology
- Indication
Not Available
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Contraindications & Blackbox WarningsWith our commercial data, access important information on dangerous risks, contraindications, and adverse effects.Our Blackbox Warnings cover Risks, Contraindications, and Adverse Effects- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Comprehensive & structured drug product infoFrom application numbers to product codes, connect different identifiers through our commercial datasets.Easily connect various identifiers back to our datasets- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Ginsamin Power Octacosanol (3 mg/1) + Ginkgo biloba (80.4 mg/1) + Panax ginseng whole (118.2 mg/1) + Zinc (5.4 mg/1) Tablet Oral Biogrand Co., Ltd 2010-03-07 Not applicable US 
- Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Ginsamin Power Octacosanol (3 mg/1) + Ginkgo biloba (80.4 mg/1) + Panax ginseng whole (118.2 mg/1) + Zinc (5.4 mg/1) Tablet Oral Biogrand Co., Ltd 2010-03-07 Not applicable US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as fatty alcohols. These are aliphatic alcohols consisting of a chain of a least six carbon atoms.
- Kingdom
- Organic compounds
- Super Class
- Lipids and lipid-like molecules
- Class
- Fatty Acyls
- Sub Class
- Fatty alcohols
- Direct Parent
- Fatty alcohols
- Alternative Parents
- Primary alcohols / Hydrocarbon derivatives
- Substituents
- Alcohol / Aliphatic acyclic compound / Fatty alcohol / Hydrocarbon derivative / Organic oxygen compound / Organooxygen compound / Primary alcohol
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- long-chain primary fatty alcohol, fatty alcohol 28:0 (CHEBI:28243) / Fatty alcohols (LMFA05000003) / a long-chain alcohol, a primary alcohol, a fatty alcohol (CPD-7872)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 81I2215OVK
- CAS number
- 557-61-9
- InChI Key
- CNNRPFQICPFDPO-UHFFFAOYSA-N
- InChI
- InChI=1S/C28H58O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29/h29H,2-28H2,1H3
- IUPAC Name
- octacosan-1-ol
- SMILES
- CCCCCCCCCCCCCCCCCCCCCCCCCCCCO
References
- General References
- Taylor JC, Rapport L, Lockwood GB: Octacosanol in human health. Nutrition. 2003 Feb;19(2):192-5. [Article]
- External Links
- Human Metabolome Database
- HMDB0034380
- KEGG Compound
- C08387
- PubChem Compound
- 68406
- PubChem Substance
- 347827945
- ChemSpider
- 61689
- 12166
- ChEBI
- 28243
- ChEMBL
- CHEMBL1951714
- ZINC
- ZINC000008221075
- PDBe Ligand
- O8N
- Wikipedia
- 1-Octacosanol
- PDB Entries
- 5tvi
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count Not Available Completed Treatment High Cholesterol 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule Oral Tablet Oral Capsule Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 1.25e-05 mg/mL ALOGPS logP 10.25 ALOGPS logP 11.47 ChemAxon logS -7.5 ALOGPS pKa (Strongest Acidic) 16.84 ChemAxon pKa (Strongest Basic) -2 ChemAxon Physiological Charge 0 ChemAxon Hydrogen Acceptor Count 1 ChemAxon Hydrogen Donor Count 1 ChemAxon Polar Surface Area 20.23 Å2 ChemAxon Rotatable Bond Count 26 ChemAxon Refractivity 132.56 m3·mol-1 ChemAxon Polarizability 60.17 Å3 ChemAxon Number of Rings 0 ChemAxon Bioavailability 0 ChemAxon Rule of Five No ChemAxon Ghose Filter No ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available Mass Spectrum (Electron Ionization) MS splash10-0a5c-9200000000-d4468fe1021d0799c6d5 Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-01ox-0019600000-845b2a7dd4bb712ef7b5 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-0006-3459200000-7d4ea0ce8ec306880a4f Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-052f-5964000000-dfc15a4fc90a524158ff Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-0a4i-0003900000-79a6dbdbe8e2769811a8 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-0a4i-1009800000-b1f2b2bd96e29dc484ea Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-002f-8559000000-718f819a53882d7149b4 1H NMR Spectrum 1D NMR Not Applicable 13C NMR Spectrum 1D NMR Not Applicable
Drug created on December 03, 2015 16:51 / Updated on June 12, 2020 16:53