This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Octacosanol
- DrugBank Accession Number
- DB11220
- Background
1-octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. This high–molecular-weight organic compound is the main component of a natural product wax extracted from plants 1. 1-octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytoprotective use, and ergogenic properties 1. It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease.
- Type
- Small Molecule
- Groups
- Nutraceutical
- Structure
Structure for Octacosanol (DB11220)
- Weight
- Average: 410.7595
Monoisotopic: 410.448766478 - Chemical Formula
- C28H58O
- Synonyms
- 1-Octacosanol
- cluytyl alcohol
- montanyl alcohol
- n-octacosanol
- Octacosanol
- Octacosyl alcohol
- External IDs
- NSC-10770
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image EUROBIO® CHOLENOL SOFT CAPSULE Capsule 80 % Oral EUROBIO SDN BHD 2020-09-08 2024-08-30 Malaysia 
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Ginsamin Power Octacosanol (3 mg/1) + Ginkgo biloba (80.4 mg/1) + Ginseng (118.2 mg/1) + Zinc (5.4 mg/1) Tablet Oral Biogrand Co., Ltd 2010-03-07 Not applicable US 
SOLARAY OCTAPOWER CAPSULE Octacosanol (2000 µg) + Bee pollen (200 mg) + Eleuthero (137.5 mg) + Ginger (25 mg) Capsule Oral PATHLAB HEALTHCARE (MALAYSIA) SDN. BHD. 2020-09-08 2024-02-24 Malaysia - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Ginsamin Power Octacosanol (3 mg/1) + Ginkgo biloba (80.4 mg/1) + Ginseng (118.2 mg/1) + Zinc (5.4 mg/1) Tablet Oral Biogrand Co., Ltd 2010-03-07 Not applicable US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as fatty alcohols. These are aliphatic alcohols consisting of a chain of a least six carbon atoms.
- Kingdom
- Organic compounds
- Super Class
- Lipids and lipid-like molecules
- Class
- Fatty Acyls
- Sub Class
- Fatty alcohols
- Direct Parent
- Fatty alcohols
- Alternative Parents
- Primary alcohols / Hydrocarbon derivatives
- Substituents
- Alcohol / Aliphatic acyclic compound / Fatty alcohol / Hydrocarbon derivative / Organic oxygen compound / Organooxygen compound / Primary alcohol
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- long-chain primary fatty alcohol, fatty alcohol 28:0 (CHEBI:28243) / Fatty alcohols (LMFA05000003) / a long-chain alcohol, a primary alcohol, a fatty alcohol (CPD-7872)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 81I2215OVK
- CAS number
- 557-61-9
- InChI Key
- CNNRPFQICPFDPO-UHFFFAOYSA-N
- InChI
- InChI=1S/C28H58O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29/h29H,2-28H2,1H3
- IUPAC Name
- octacosan-1-ol
- SMILES
- CCCCCCCCCCCCCCCCCCCCCCCCCCCCO
References
- General References
- Taylor JC, Rapport L, Lockwood GB: Octacosanol in human health. Nutrition. 2003 Feb;19(2):192-5. [Article]
- External Links
- Human Metabolome Database
- HMDB0034380
- KEGG Compound
- C08387
- PubChem Compound
- 68406
- PubChem Substance
- 347827945
- ChemSpider
- 61689
- 12166
- ChEBI
- 28243
- ChEMBL
- CHEMBL1951714
- ZINC
- ZINC000008221075
- PDBe Ligand
- O8N
- Wikipedia
- 1-Octacosanol
- PDB Entries
- 5tvi
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample dataNot Available Completed Treatment High Cholesterol 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule Oral 80 % Tablet Oral Capsule Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 1.25e-05 mg/mL ALOGPS logP 10.25 ALOGPS logP 11.47 Chemaxon logS -7.5 ALOGPS pKa (Strongest Acidic) 16.84 Chemaxon pKa (Strongest Basic) -2 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 20.23 Å2 Chemaxon Rotatable Bond Count 26 Chemaxon Refractivity 132.56 m3·mol-1 Chemaxon Polarizability 60.17 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 270.5318107 predictedDarkChem Lite v0.1.0 [M-H]- 270.8339107 predictedDarkChem Lite v0.1.0 [M-H]- 269.2458107 predictedDarkChem Lite v0.1.0 [M-H]- 202.46844 predictedDeepCCS 1.0 (2019) [M+H]+ 272.0314107 predictedDarkChem Lite v0.1.0 [M+H]+ 271.3019107 predictedDarkChem Lite v0.1.0 [M+H]+ 270.9282107 predictedDarkChem Lite v0.1.0 [M+H]+ 205.01877 predictedDeepCCS 1.0 (2019) [M+Na]+ 271.3507107 predictedDarkChem Lite v0.1.0 [M+Na]+ 269.8982107 predictedDarkChem Lite v0.1.0 [M+Na]+ 270.1500107 predictedDarkChem Lite v0.1.0 [M+Na]+ 211.36166 predictedDeepCCS 1.0 (2019)
Drug created at December 03, 2015 16:51 / Updated at June 12, 2020 16:53