Dioxybenzone is a benzophenone derivative used in sunscreens to block UVB and short-wave UVA radiation. Dioxybenzone, or benzophenone-8, is an organic compound derived from DB01878 that is used as a sunscreen agent.
- Mechanism
- Curator reviewed · 2 references
Emitted by the sun, UVA-II rays, which range at 320–400 nm and are not absorbed by the ozone layer, and UVB rays, which range 290–320 nm and are partially absorbed by the ozone layer and exert a damaging effect on human skin, including basal cell carcinoma and melanoma. As a chemical filter, dioxybenzone absorb these rays to prevent their penetration into the skin and attenuate long-term skin damage caused by UV radiation from the sun. In a rat uterine cytosolic estrogen receptor (ER) competitive binding assay, dioxybenzone was not found to be a ER-binder.
- Primary indication
- Indicated for use as an active sunscreen agent.Curator reviewed · 1 structured indication
- Formula / weight
- C14H12O4 · 244.246 g/mol (avg)
- First approval
- Canada, 1997
- Code names
- NSC-56769
Resolves to
MEZZCSHVIGVWFI-UHFFFAOYSA-NSMILESCOC1=CC(O)=C(C=C1)C(=O)C1=CC=CC=C1OWhat you can answer from here — as of March 06, 2025
Which drugs share a target with Dioxybenzone, and which of those have an active Phase 3 trial?
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