This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Poliglusam
DrugBank Accession Number
DB11234
Background

Poliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from degradation of chitin induced by certain groups of bacteria that produce the enzymes deacetylase or chitosanase enzymes 1. In comparison, commercial poliglusam is derived from deacetylation of chitin contained in the shells of various sea crustaceans such as shrimps 1. As a rich source of dietary fiber, chitosan is used as a food ingredient or additive. It is also reported to have an effect on protein aggregation, emulsification capacity, film-forming ability, clarifying ability, and fatty acid absorption capability 1. In addition, chitosan also exhibits antimicrobial and antioxidant activities.

Type
Small Molecule
Groups
Experimental
Synonyms
  • Chitosan medium molecular weight (200-800 mpa.s)
  • Poliglusam

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug events
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
Technetium Tc-99m oxidronatePoliglusam may decrease effectiveness of Technetium Tc-99m oxidronate as a diagnostic agent.
Identify potential medication risks
Easily compare up to 40 drugs with our drug interaction checker.
Get severity rating, description, and management advice.
Learn more
Food Interactions
Not Available

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Ceravida FreshLiquid5 kg/100kgTopicalG.CLO CO., LTD2020-06-02Not applicableUS flag
Cotton pieceCloth0.01 g/1000gTopicalQingdao Miuton Medical Co.,LTD.2020-08-05Not applicableUS flag
U-max BeautySoap1 g/100gTopicalVS Shinbi Co., Ltd.2012-06-12Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Ceravida FreshPoliglusam (5 kg/100kg)LiquidTopicalG.CLO CO., LTD2020-06-02Not applicableUS flag
Cotton piecePoliglusam (0.01 g/1000g)ClothTopicalQingdao Miuton Medical Co.,LTD.2020-08-05Not applicableUS flag
U-max BeautyPoliglusam (1 g/100g)SoapTopicalVS Shinbi Co., Ltd.2012-06-12Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
82LKS4QV2Y
CAS number
9012-76-4

References

General References
  1. FDA Packaging label: Shrimp-derived chitosan [Link]
PubChem Substance
347911159
RxNav
1368152

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Tablet
LiquidTopical5 kg/100kg
CapsuleOral500 MG
ClothTopical0.01 g/1000g
CapsuleOral250 mg
CapsuleOral
SoapTopical1 g/100g
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at December 03, 2015 16:51 / Updated at February 21, 2021 18:53