This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Poliglusam
- DrugBank Accession Number
- DB11234
- Background
Poliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from degradation of chitin induced by certain groups of bacteria that produce the enzymes deacetylase or chitosanase enzymes 1. In comparison, commercial poliglusam is derived from deacetylation of chitin contained in the shells of various sea crustaceans such as shrimps 1. As a rich source of dietary fiber, chitosan is used as a food ingredient or additive. It is also reported to have an effect on protein aggregation, emulsification capacity, film-forming ability, clarifying ability, and fatty acid absorption capability 1. In addition, chitosan also exhibits antimicrobial and antioxidant activities.
- Type
- Small Molecule
- Groups
- Experimental
- Synonyms
- Chitosan medium molecular weight (200-800 mpa.s)
- Poliglusam
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareTechnetium Tc-99m oxidronate Poliglusam may decrease effectiveness of Technetium Tc-99m oxidronate as a diagnostic agent. - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Ceravida Fresh Liquid 5 kg/100kg Topical G.CLO CO., LTD 2020-06-02 Not applicable US 
Cotton piece Cloth 0.01 g/1000g Topical Qingdao Miuton Medical Co.,LTD. 2020-08-05 Not applicable US U-max Beauty Soap 1 g/100g Topical VS Shinbi Co., Ltd. 2012-06-12 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Ariella Nail Repair Pen Poliglusam (2 g/100mL) + Salicylic acid (3 g/100mL) Liquid Topical YITONGBADA (SHENZHEN) INTERNATIONAL TRADE CO., LTD 2023-05-12 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Ariella Nail Repair Pen Poliglusam (2 g/100mL) + Salicylic acid (3 g/100mL) Liquid Topical YITONGBADA (SHENZHEN) INTERNATIONAL TRADE CO., LTD 2023-05-12 Not applicable US Ceravida Fresh Poliglusam (5 kg/100kg) Liquid Topical G.CLO CO., LTD 2020-06-02 Not applicable US Cotton piece Poliglusam (0.01 g/1000g) Cloth Topical Qingdao Miuton Medical Co.,LTD. 2020-08-05 Not applicable US U-max Beauty Poliglusam (1 g/100g) Soap Topical VS Shinbi Co., Ltd. 2012-06-12 Not applicable US
Categories
- Drug Categories
- Anticholesteremic Agents
- Biocompatible Materials
- Biopolymers
- Carbohydrates
- Chelating Agents
- Chitin
- Chitosan
- Coagulants
- Compounds used in a research, industrial, or household setting
- Hematologic Agents
- Hemostatics
- Hypolipidemic Agents
- Lipid Regulating Agents
- Macromolecular Substances
- Polymers
- Polysaccharides
- Sequestering Agents
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 82LKS4QV2Y
- CAS number
- 9012-76-4
References
- General References
- FDA Packaging label: Shrimp-derived chitosan [Link]
- External Links
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet Liquid Topical Liquid Topical 5 kg/100kg Capsule Oral 500 MG Cloth Topical 0.01 g/1000g Capsule Oral 250 mg Capsule Oral Soap Topical 1 g/100g - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at December 03, 2015 16:51 / Updated at February 21, 2021 18:53