Protocatechualdehyde

DB11268ApprovedSmall molecule

Also known as protocatechuic aldehyde, protocatechualdehyde is a naturally-occuring phenolic aldehyde that is found in barley, green cavendish bananas, grapevine leaves and root of the herb S. miltiorrhiza . Protocatechualdehyde... Protocatechualdehyde possesses antiproliferative and pro-apoptotic properties against human breast cancer cells and colorectal cancer cells by reducing the expression of pro-oncogenes β-catenin and cyclin D1.

Chemical structure of Protocatechualdehyde
Formula / weight
C7H6O3 · 138.1207 g/mol (avg)
Also known as
3,4-dihydroxybenzaldehyde · Protocatechuic aldehyde · Rancinamycin IV
Code names
NSC-22961

Resolves to

Compound
UNII4PVP2HCH4TCAS139-85-5ChEMBLCHEMBL222021ChEBI50205PubChem8768KEGGC16700
Clinical / RWD
RxNorm1362689
Structure
InChIKeyIBGBGRVKPALMCQ-UHFFFAOYSA-NSMILES[H]C(=O)C1=CC(O)=C(O)C=C1
Targets
P27338MAOB

What you can answer from here — as of March 12, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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140Drug interactionsStructured to mechanism, not free text
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2Marketed productsAcross 1 country and 1 labeller
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Protocatechualdehyde, and which of those have an active Phase 3 trial?

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