DB11327ApprovedSmall molecule
Dipyrithione, a bactericidal and fungicidal pyrithione derivate, was formulated as Crimanex anti-dandruff shampoo, but is no longer available. It is currently used as a pesticide, and not used in any... Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum antitumor activity, which suggests a potential basis for an anticancer drug development.
- Mechanism
- Curator reviewed · 3 references
This drug is a fungicidal agent. Fungicide, also called antimycotic, any toxic substance used to kill or inhibit the growth of fungi.
- Primary indication
- Scalp dandruffCurator reviewed · 2 structured indications
- Formula / weight
- C10H8N2O2S2 · 252.31 g/mol (avg)
- First approval
- Canada, 1994
- Also known as
- Bispyrithione · Omadine disulfide · OMDS · Pyrithione disulfide · Pyrithione disulphide
- Code names
- OSY 20
Resolves to
Clinical / RWD
Structure
InChIKey
ZHDBTKPXEJDTTQ-UHFFFAOYSA-NSMILES[O-][N+]1=CC=CC=C1SSC1=CC=CC=[N+]1[O-]Targets
What you can answer from here — as of September 23, 2026
2Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Dipyrithione, and which of those have an active Phase 3 trial?
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