Zeatin
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Zeatin
- DrugBank Accession Number
- DB11337
- Background
An aminopurine factor in plant extracts that induces cell division. (Grant & Hackh's Chemical Dict, 5th ed)
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 219.2431
Monoisotopic: 219.112010063 - Chemical Formula
- C10H13N5O
- Synonyms
- (E)-2-methyl-4-(1H-purin-6-ylamino)-2-buten-1-ol
- (E)-2-methyl-4-(1H-purin-6-ylamino)but-2-en-1-ol
- (E)-2-methyl-4-(purin-6-ylamino)-2-buten-1-ol
- (E)-zeatin
- N6-(4-Hydroxyisopentenyl)adenine
- trans-Zeatin
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ObagiGentle Rejuvenati Gentle Rejuvenation Zeatin (.03 mg/30g) + Kinetin (.03 mg/30g) Lotion Topical YS PLUS CORPORATION 2014-10-01 2015-12-31 US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ObagiGentle Rejuvenati Gentle Rejuvenation Zeatin (.03 mg/30g) + Kinetin (.03 mg/30g) Lotion Topical YS PLUS CORPORATION 2014-10-01 2015-12-31 US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as 6-alkylaminopurines. These are compounds that contain an alkylamine group attached at the 6-position of a purine. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Imidazopyrimidines
- Sub Class
- Purines and purine derivatives
- Direct Parent
- 6-alkylaminopurines
- Alternative Parents
- Secondary alkylarylamines / Aminopyrimidines and derivatives / Imidolactams / Imidazoles / Heteroaromatic compounds / Azacyclic compounds / Primary alcohols / Organopnictogen compounds / Hydrocarbon derivatives
- Substituents
- 6-alkylaminopurine / Alcohol / Amine / Aminopyrimidine / Aromatic heteropolycyclic compound / Azacycle / Azole / Heteroaromatic compound / Hydrocarbon derivative / Imidazole
- Molecular Framework
- Aromatic heteropolycyclic compounds
- External Descriptors
- zeatin (CHEBI:16522)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 7I6OOJ9GR6
- CAS number
- 1637-39-4
- InChI Key
- UZKQTCBAMSWPJD-FARCUNLSSA-N
- InChI
- InChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+
- IUPAC Name
- (2E)-2-methyl-4-[(7H-purin-6-yl)amino]but-2-en-1-ol
- SMILES
- C\C(CO)=C/CNC1=C2N=CNC2=NC=N1
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0012204
- KEGG Compound
- C00371
- ChemSpider
- 395716
- BindingDB
- 227637
- 1440227
- ChEBI
- 16522
- ChEMBL
- CHEMBL525239
- ZINC
- ZINC000004492895
- PDBe Ligand
- ZEA
- Wikipedia
- Zeatin
- PDB Entries
- 1w1r / 2flh / 2qim / 3c0v / 3d7w / 3t4l / 3t4q / 4jhg / 4ryv / 5mxw … show 2 more
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Lotion Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.283 mg/mL ALOGPS logP 0.49 ALOGPS logP -0.19 Chemaxon logS -2.9 ALOGPS pKa (Strongest Acidic) 10.21 Chemaxon pKa (Strongest Basic) 3.46 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 86.72 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 64.61 m3·mol-1 Chemaxon Polarizability 22.93 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 162.4404586 predictedDarkChem Lite v0.1.0 [M-H]- 162.3651586 predictedDarkChem Lite v0.1.0 [M-H]- 160.8674586 predictedDarkChem Lite v0.1.0 [M-H]- 149.13835 predictedDeepCCS 1.0 (2019) [M+H]+ 163.3968586 predictedDarkChem Lite v0.1.0 [M+H]+ 163.2172586 predictedDarkChem Lite v0.1.0 [M+H]+ 161.7098586 predictedDarkChem Lite v0.1.0 [M+H]+ 151.49637 predictedDeepCCS 1.0 (2019) [M+Na]+ 163.1832586 predictedDarkChem Lite v0.1.0 [M+Na]+ 162.5117586 predictedDarkChem Lite v0.1.0 [M+Na]+ 158.3798 predictedDeepCCS 1.0 (2019)
Drug created at December 03, 2015 16:52 / Updated at June 12, 2020 16:53