Zeatin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Zeatin
DrugBank Accession Number
DB11337
Background

An aminopurine factor in plant extracts that induces cell division. (Grant & Hackh's Chemical Dict, 5th ed)

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 219.2431
Monoisotopic: 219.112010063
Chemical Formula
C10H13N5O
Synonyms
  • (E)-2-methyl-4-(1H-purin-6-ylamino)-2-buten-1-ol
  • (E)-2-methyl-4-(1H-purin-6-ylamino)but-2-en-1-ol
  • (E)-2-methyl-4-(purin-6-ylamino)-2-buten-1-ol
  • (E)-zeatin
  • N6-(4-Hydroxyisopentenyl)adenine
  • trans-Zeatin

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products
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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ObagiGentle Rejuvenati Gentle RejuvenationZeatin (.03 mg/30g) + Kinetin (.03 mg/30g)LotionTopicalYS PLUS CORPORATION2014-10-012015-12-31US flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ObagiGentle Rejuvenati Gentle RejuvenationZeatin (.03 mg/30g) + Kinetin (.03 mg/30g)LotionTopicalYS PLUS CORPORATION2014-10-012015-12-31US flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as 6-alkylaminopurines. These are compounds that contain an alkylamine group attached at the 6-position of a purine. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Imidazopyrimidines
Sub Class
Purines and purine derivatives
Direct Parent
6-alkylaminopurines
Alternative Parents
Secondary alkylarylamines / Aminopyrimidines and derivatives / Imidolactams / Imidazoles / Heteroaromatic compounds / Azacyclic compounds / Primary alcohols / Organopnictogen compounds / Hydrocarbon derivatives
Substituents
6-alkylaminopurine / Alcohol / Amine / Aminopyrimidine / Aromatic heteropolycyclic compound / Azacycle / Azole / Heteroaromatic compound / Hydrocarbon derivative / Imidazole
Molecular Framework
Aromatic heteropolycyclic compounds
External Descriptors
zeatin (CHEBI:16522)
Affected organisms
Not Available

Chemical Identifiers

UNII
7I6OOJ9GR6
CAS number
1637-39-4
InChI Key
UZKQTCBAMSWPJD-FARCUNLSSA-N
InChI
InChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+
IUPAC Name
(2E)-2-methyl-4-[(7H-purin-6-yl)amino]but-2-en-1-ol
SMILES
C\C(CO)=C/CNC1=C2N=CNC2=NC=N1

References

General References
Not Available
Human Metabolome Database
HMDB0012204
KEGG Compound
C00371
ChemSpider
395716
BindingDB
227637
RxNav
1440227
ChEBI
16522
ChEMBL
CHEMBL525239
ZINC
ZINC000004492895
PDBe Ligand
ZEA
Wikipedia
Zeatin
PDB Entries
1w1r / 2flh / 2qim / 3c0v / 3d7w / 3t4l / 3t4q / 4jhg / 4ryv / 5mxw

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LotionTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.283 mg/mLALOGPS
logP0.49ALOGPS
logP-0.19ChemAxon
logS-2.9ALOGPS
pKa (Strongest Acidic)10.21ChemAxon
pKa (Strongest Basic)3.46ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count5ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area86.72 Å2ChemAxon
Rotatable Bond Count4ChemAxon
Refractivity64.61 m3·mol-1ChemAxon
Polarizability22.93 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
GC-MS Spectrum - GC-MS (3 TMS)GC-MSsplash10-0uea-3669000000-71f80cf16f89ded4787a
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
GC-MS Spectrum - GC-MSGC-MSsplash10-0uea-3669000000-71f80cf16f89ded4787a
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available
LC-MS/MS Spectrum - LC-ESI-qTof , PositiveLC-MS/MSNot Available
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-014i-0090000000-860e5e26a7c78621ff1b
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-0159-0890000000-e0d9da4d76a19fdcc38e
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-001i-0900000000-73c2883cf4c5c86e5202
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-001i-0900000000-40634e98d8610da6da7e
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-001i-1900000000-f685d83e661ba76c7b5f
LC-MS/MS Spectrum - LC-ESI-QTOF , negativeLC-MS/MSsplash10-00lr-0940000000-cb6bb2cc6e09e94bf9e9
LC-MS/MS Spectrum - LC-ESI-QTOF , negativeLC-MS/MSsplash10-014i-0490000000-7a274998c68b723d3fb6
LC-MS/MS Spectrum - LC-ESI-QTOF , negativeLC-MS/MSsplash10-001i-0910000000-92dd3eccb6d6c8cf56b7
LC-MS/MS Spectrum - LC-ESI-QTOF , negativeLC-MS/MSsplash10-001i-0900000000-916fa5a85cf88a795576
MS/MS Spectrum - Linear Ion Trap , negativeLC-MS/MSsplash10-0udr-0980000000-3b6cbd9a900a91cda1ec
MS/MS Spectrum - Linear Ion Trap , negativeLC-MS/MSsplash10-0udr-0890000000-615009ba0eecc0c276f7
MS/MS Spectrum - Linear Ion Trap , negativeLC-MS/MSsplash10-014i-0090000000-74ba65be8d88785a72a9
MS/MS Spectrum - Linear Ion Trap , negativeLC-MS/MSsplash10-014i-0090000000-17f89903bb26df54893d
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-00di-0090000000-dd1e015f41cf26595e40
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-0079-0980000000-71f5c1676966e90a2d17
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-000i-0900000000-59732140535260402378
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-000i-3900000000-76812b403415131902a1
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-014l-5900000000-e13e6e9ecfdac2ef5cf7
LC-MS/MS Spectrum - LC-ESI-IT , positiveLC-MS/MSsplash10-0udr-0980000000-2e91e9251b00df2a9a5a
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-052r-0940000000-72d0ea8792915decf405
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-0f79-0980000000-60d68393d177a1204176
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-014i-0390000000-f6c254005213ff8459e1
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-000i-0900000000-413ec7543121f4ee90dd
LC-MS/MS Spectrum - LC-ESI-QQ , positiveLC-MS/MSsplash10-00kr-1900000000-a4a929f06958947235bb
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-000i-0940000000-cb0bbc57cc639674a102
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-0079-0950000000-0bbcc9cbac2318c1347d
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-000i-0900000000-a7851763816b8e910557
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-014i-0900000000-f6d5739f59d3ec015ed2
MS/MS Spectrum - Linear Ion Trap , positiveLC-MS/MSsplash10-0f7a-0940000000-6fd2e30ceb499e456247
MS/MS Spectrum - Linear Ion Trap , positiveLC-MS/MSsplash10-0f7a-0940000000-0a6aacb55f9ecf96cfd1
MS/MS Spectrum - , positiveLC-MS/MSsplash10-000i-0900000000-c0d1c2cc02d66d524c5e
1H NMR Spectrum1D NMRNot Applicable
13C NMR Spectrum1D NMRNot Applicable

Drug created on December 03, 2015 16:52 / Updated on June 12, 2020 16:53