This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Cocamidopropyl betaine
DrugBank Accession Number
DB11350
Background

Cocamidopropyl betaine is a mixture of closely related organic compounds derived from coconut oil and dimethylaminopropylamine that typically acts as an amphoteric surfactant in cosmetics and personal care products. It is a zwitterionic ammonium compound and fatty acid amide that contains a long hydrocarbon chain and a polar group at each end. Cocamidopropyl betaine is used as a foam booster in shampoos, emulsifying agent, thickener, antistatic agent and rarely an antiseptic agent. Impurities formed during the manufacturing process are thought to increase the prevalence of contact sensitization and mild skin irritations.

Type
Small Molecule
Groups
Experimental
Synonyms
Not Available

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products2
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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Argan Essential Deep CareShampoo72 mg/300mLTopicalNature Republic Co., Ltd.2015-09-012018-12-01US flag
Balmers Hanryeoncho WShampoo24 g/100mLTopicalTae Eul Bi Co., Ltd.2015-07-20Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Hand SanitizerCocamidopropyl betaine (5 1/100g) + Citric acid monohydrate (0.3 g/100g)LiquidTopicalNINGBO JIANGBEI OCEAN STAR TRADING CO.,LTD2016-09-26Not applicableUS flag
Yenaya Secret Gung CleanserCocamidopropyl betaine (8 mg/100mL) + Lactic acid (1 mg/100mL)GelTopicalIFACKOREA CO., LTD2021-05-04Not applicableUS flag
Yenaya Secret Gung CleanserCocamidopropyl betaine (8 mg/100mL) + Lactic acid (1 mg/100mL)GelTopicalIFACKOREA CO., LTD2021-05-06Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Argan Essential Deep CareCocamidopropyl betaine (72 mg/300mL)ShampooTopicalNature Republic Co., Ltd.2015-09-012018-12-01US flag
Balmers Hanryeoncho WCocamidopropyl betaine (24 g/100mL)ShampooTopicalTae Eul Bi Co., Ltd.2015-07-20Not applicableUS flag
Yenaya Secret Gung CleanserCocamidopropyl betaine (8 mg/100mL) + Lactic acid (1 mg/100mL)GelTopicalIFACKOREA CO., LTD2021-05-06Not applicableUS flag
Yenaya Secret Gung CleanserCocamidopropyl betaine (8 mg/100mL) + Lactic acid (1 mg/100mL)GelTopicalIFACKOREA CO., LTD2021-05-04Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
5OCF3O11KX
CAS number
61789-40-0

References

General References
  1. Jacob SE, Amini S: Cocamidopropyl betaine. Dermatitis. 2008 May-Jun;19(3):157-60. [Article]
PubChem Substance
347911193
RxNav
1311576
Wikipedia
Cocamidopropyl_betaine

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
ShampooTopical72 mg/300mL
ShampooTopical24 g/100mL
LiquidTopical
GelTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at December 03, 2015 16:52 / Updated at June 12, 2020 16:53