Eprinomectin

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DB11405ExperimentalVet approvedSmall molecule

Eprinomectin: Overview.

Mechanism: Pharmacologically active on Glutamate-gated chloride channel
Curator reviewed
Formula / weight: C₄₉H₇₃NO₁₄ · 900.116 g/mol (avg)
Code names: MK-397

Resolves to

Compound

UNII75KP30FD8OCAS123997-26-2KEGGD04037

Clinical / RWD

RxNorm1006619

Structure

InChIKeyWPNHOHPRXXCPRA-TVXIRPTOSA-NSMILES

[H]O[C@@H]1C(C)=C[C@@]2([H])C(=O)O[C@@]3([H])C[C@@]([H])(C\C=C(C)/[C@@H](O[C@H]4C[C@H](OC)[C@H](O[C@H]5C[C@@H](OC)[C@H](N([H])C(C)=O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C/C=C4/CO[C@@]1([H])[C@]24O[H])O[C@@]1(C3)O[C@H](C(C)C)[C@@H](C)C=C1

Targets

Q25634GluClX

Transporters

P08183ABCB1Q9UNQ0ABCG2

What you can answer from here — as of September 14, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2TransportersSubstrate / inhibitor direction, not just membership

Listed above

317Drug interactionsStructured to mechanism, not free text

15+ReferencesStructured and connected to the statements they support

Which drugs share a target with Eprinomectin, and which of those have an active Phase 3 trial?

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