Sarafloxacin

DB11491ApprovedVet approvedWithdrawnSmall molecule

Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.

Mechanism: Pharmacologically active on DNA gyrase subunit A
Curator reviewed
Formula / weight: C₂₀H₁₇F₂N₃O₃ · 385.3641 g/mol (avg)
Code names: ABBOTT-57135

Resolves to

Compound

UNIIRC3WJ907XYCAS98105-99-8ChEMBLCHEMBL37858ChEBI94493PubChem56208

Structure

InChIKeyXBHBWNFJWIASRO-UHFFFAOYSA-NSMILESOC(=O)C1=CN(C2=CC=C(F)C=C2)C2=CC(N3CCNCC3)=C(F)C=C2C1=O

Targets

P0AES4gyrA

What you can answer from here — as of September 16, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

958Drug interactionsStructured to mechanism, not free text

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Sarafloxacin, and which of those have an active Phase 3 trial?

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