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Rabies immune globulin, human is a solution of antibodies used to prevent rabies after an exposure. IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced rabies vaccine.
- Mechanism
- Curator reviewed
Rabies immune globulin binds the rabies virus, preventing it from invading the central nervous system. This affords time for the rabies vaccine, which is also administered in cases of rabies exposure, to induce an immune response to destroy the virus. Rabies immunoglobulin should only be administered up to eight days after exposure as the host begins to produce sufficient antibodies to the virus one week after exposure. Repeat dosing should also be avoided as it may interfere with induction of immune response by the rabies vaccine.
- Primary indication
- The human rabies immune globulin is used indicated for passive, transient post-exposure prophylaxis of rabies infection to persons of all ages when given immediately after contact with a rabid or possibly rabid animal.Curator reviewed · 1 structured indication
- First approval
- Canada, 2005 · United States, 1974
- Also known as
- Human rabies virus immune globulin · Rabies immune globulin · Rabies immune globulin (human) · Rabies immune globulin human · Rabies immune globulin,human
- Brand names
- Hyperrab
- Imogam
- Kedrab
- Rabavert
Resolves to
What you can answer from here — as of November 20, 2025
Which other approved drugs treat the same conditions as Rabies immune globulin, human, and which companies have late-stage candidates in those indications?