QAV-680

DB11658InvestigationalSmall molecule

QAV680 has been used in trials studying the treatment of Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis.

Chemical structure of QAV-680
Mechanism
Curator reviewed
Formula / weight
C18H18N2O4S · 358.41 g/mol (avg)
Code names
NVP-QAV680 · QAV680 · QAV690 FREE ACID

Resolves to

Compound
UNII0E3D72URPDCAS872365-16-7ChEMBLCHEMBL2442750PubChem11508736
Structure
InChIKeyYOPFAMROKXHVCQ-UHFFFAOYSA-NSMILESCC1=C(CC(O)=O)C2=CC=CN=C2N1CC1=CC=C(C=C1)S(C)(=O)=O
Targets
Q9Y5Y4PTGDR2

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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4Clinical trialsPhase, status and sponsor resolved per trial
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with QAV-680, and which of those have an active Phase 3 trial?

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