Tofimilast

DB11681InvestigationalSmall molecule

Tofimilast has been used in trials studying the treatment of Asthma and Pulmonary Disease, Chronic Obstructive.

Chemical structure of Tofimilast
Mechanism
Curator reviewed
Formula / weight
C18H21N5S · 339.46 g/mol (avg)

Resolves to

Compound
UNII5D7022962ACAS185954-27-2ChEMBLCHEMBL217899PubChem9896267
Structure
InChIKeyDHCOPPHTVOXDKU-UHFFFAOYSA-NSMILESCCC1=NN(C2CCCC2)C2=C1CCN1C(=NN=C21)C1=CC=CS1
Targets
P27815PDE4AQ08499PDE4DQ07343PDE4B

What you can answer from here — as of June 15, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
2Clinical trialsPhase, status and sponsor resolved per trial
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12+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Tofimilast, and which of those have an active Phase 3 trial?

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