Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.
- Mechanism
- Curator reviewed
Dendrimers such as astodrimer are polymers that contain a central core, interior branches, and terminal surface groups adapted to specific targets. Astodrimer has a polyanionic outer surface that provides for multiple target interactions. The active surface groups bind to gp120 proteins on HIV's surface, preventing CD4 receptor binding by healthy cells and thus blocking transmission of HIV to healthy cells.
- Also known as
- Vivagel
- Code names
- BRI-7013 · SPL-7013
Resolves to
What you can answer from here — as of July 17, 2026
Which drugs share a target with Astodrimer, and which of those have an active Phase 3 trial?
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